My daughter has food allergies, mesenteric adenitis, and tubular adenoma. Please help.

Question

Hi doctor,

My daughter is an 11-year-old female and has a history of multiple food sensitivities, bloating, stool with pieces of unprocessed food with elevated serum serotonin, and three episodes of mesenteric adenitis. I have sent you the endoscopy and colonoscopy biopsy results. Can you please help me with this?

Kindly help.

Answer 1

Hello,

Welcome to icliniq.com.

I reviewed all the biopsy reports (attachment removed to protect the patient's identity), the reports are all normal except for one rectal polyp. Also, there are no findings suggestive of any allergic disorders, especially food allergies or eosinophilic enteritis. These biopsies have no clues for loose stools. In my opinion, there are no significant abnormalities in these reports to explain her complaints.

If you have any query get back to me with her complete blood tests and detailed history.

Thank you very much.

Answer 2

Hi,

Welcome back to icliniq.com.

I understand your concern about your child. These are my suggestions about your query:

As seen in colon biopsy, this crypt distortion is in a tiny part and is focal and the rest of all biopsies have no such findings, which makes it clinically insignificant.
I agree with you that this Adenoma with low-grade dysplasia is rare in children, but it can occur. In that case, children usually have multiple large polyps in the whole of the colon, which is not seen in her case.
And this rectal polyp is also tiny. This dysplasia looks to be over-reported, and it will need a review from an expert GI (gastrointestinal) histopathologist.
It is good that you are referred to one of the best GI centers, and it may help out in her diagnosis, and they will surely review her adenoma report.
She may be suffering from some rare syndrome, but as of now, she has no significant clue for a diagnosis.

I hope that it answers your question.

Thank you.