HomeAnswersRheumatologywegener's granulomatosisMy 28-year-old wife has been diagnosed with Wegener's granulomatosis. Is this disease curable?

What challenges can a 28-year-old married woman face due to Wegener's granulomatosis?

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The following is an actual conversation between an iCliniq user and a doctor that has been reviewed and published as a Premium Q&A.

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iCliniq medical review team

Published At September 3, 2022
Reviewed AtJuly 5, 2023

Patient's Query

Hello doctor,

I married a girl who is 28 years old now. We got married a year ago. She was diagnosed with Wegener's granulomatosis. She is taking medications and injections. I learned about the severity of the disease, so I started feeling low. I am attaching her blood work and reports. I need to know whether this disease is curable or not. If it is not curable, what challenges can she face?

Hello,

Welcome to icliniq.com.

I have seen these reports (attachments removed to protect the patient's identity) in the past also. From these reports, I can say that she is in remission, which means the disease is under control. I understand your concern as the disease is lifelong, and once it is in the remission stage, she will be normal, but relapses can occur. It is the time when treatment escalation is needed. She is on proper treatment, and her kidney and lung function is normal.

Patient's Query

Thank you doctor for the reply,

Is there any cure for this disease? I am 28 years old, and it affects my personal and professional life. I am not at all happy in this marriage. Please answer the following:

  1. What are the direct and side effects of the medication she is using?
  2. What effect will the medication have on the kids?

Hello,

Welcome back to icliniq.com.

As I said, it is a lifelong disease with no cure. Let me tell you that the tablet Azathioprine is safe during pregnancy. However, Abatacept is a new drug, and as of now, there is limited data on human pregnancy. Likewise, the tablet Methotrexate is not safe, and so it should be stopped six months before conceiving.

Patient's Query

Thank you doctor for the reply,

Please answer the following questions:

  1. What are the chances of relapses?
  2. What are the effects of long-term medications?
  3. Is this a rare disease?

Hello,

Welcome back to icliniq.com.

The chances of relapse are there, and no one can predict them. The long-term use of immunosuppressive therapy can result in infections, but they are curable, and vaccination is important to prevent infections. It is a rare disease like diabetes, but it was just an example that there is no cure for both.

Same symptoms don't mean you have the same problem. Consult a doctor now!

Dr. Ashaq Hussain Parrey
Dr. Ashaq Hussain Parrey

Rheumatology

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