Drug and Supplements Data Verified

Insulin Timing

Published on Sep 14, 2015 and last reviewed on Nov 25, 2019   -  1 min read


Many patients suffer from hypoglycemia with insulin treatment. In most cases, it is due to the lack of knowledge of insulin action.

Insulin Timing
Insulin Preparation Generic Name Onset Peak
Rapid-acting Insulin Aspart 5-10 minutes

1-3 hrs

Insulin Lispro

< 15 minutes

½-1½ hrs

Insulin Glulisine

< 15 minutes

½-1½ hrs



½-1 hr

2-3 hrs

Intermediate-acting NPH

2-4 hrs

4-10 hrs

Long-acting Insulin Glargine

1 hr

No peak


1-2 hrs

No peak


70% NPH+30% Regular

½-1 hr

There are 2 peaks: 2-3 hrs &4-10 hrs

70% Aspart Protamine +30% Aspart

5-10 minutes

There are 2 peaks: 1-3 hrs &4-10 hrs

50% Lispro Protamine +50% Lispro

< 15 minutes

There are 2 peaks: ½-1½ hrs &4-10 hrs

75% Lispro Protamine +25% Lispro

< 15 minutes

There are 2 peaks: ½-1½ hrs &4-10 hrs


Last reviewed at:
25 Nov 2019  -  1 min read




Comprehensive Medical Second Opinion.Submit your Case

Related Questions & Answers

What causes hypoglycemia?

Query: Hi doctor, My mother has been suffering from diabetes for three years. She is 61 years old and weighs 40 kg. She was on Gemer-1. Early morning around 5 AM, she often complains of excessive sweating and weakness. Sweating stops after taking tea, biscuit or sugar. She has stopped taking medication for...  Read Full »

What causes irregular periods?

Query: Hello doctor, I have been having issues of on and off periods for nearly four years now. When I started my periods, they were completely normal, neither heavy nor light and nothing unusual. But, I started missing my cycle for about six months and then I would come back completely normal. My last epi...  Read Full »

What should I do if my mom's diabetes medicine causes hypoglycemia?

Query: Hello doctor, My mother was diagnosed with type 2 diabetes. Her first blood sugar test report was at 437. Now, after three months, the fasting level is 86. Last month fasting was 105 and post-prandial was 120. She is taking half a tablet of Glimepiride 2 mg and Metformin 1000 mg both twice a day...  Read Full »

Popular Articles Most Popular Articles

Do you have a question on Insulin Timing or Hypoglycemia?

Ask a Doctor Online

* guaranteed answer within 4 hours.

Disclaimer: No content published on this website is intended to be a substitute for professional medical diagnosis, advice or treatment by a trained physician. Seek advice from your physician or other qualified healthcare providers with questions you may have regarding your symptoms and medical condition for a complete medical diagnosis. Do not delay or disregard seeking professional medical advice because of something you have read on this website.