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Insulin Timing

Published on Sep 14, 2015 and last reviewed on Nov 25, 2019   -  1 min read


Many patients suffer from hypoglycemia with insulin treatment. In most cases, it is due to the lack of knowledge of insulin action.

Insulin Timing
Insulin Preparation Generic Name Onset Peak
Rapid-acting Insulin Aspart 5-10 minutes

1-3 hrs

Insulin Lispro

< 15 minutes

½-1½ hrs

Insulin Glulisine

< 15 minutes

½-1½ hrs



½-1 hr

2-3 hrs

Intermediate-acting NPH

2-4 hrs

4-10 hrs

Long-acting Insulin Glargine

1 hr

No peak


1-2 hrs

No peak


70% NPH+30% Regular

½-1 hr

There are 2 peaks: 2-3 hrs &4-10 hrs

70% Aspart Protamine +30% Aspart

5-10 minutes

There are 2 peaks: 1-3 hrs &4-10 hrs

50% Lispro Protamine +50% Lispro

< 15 minutes

There are 2 peaks: ½-1½ hrs &4-10 hrs

75% Lispro Protamine +25% Lispro

< 15 minutes

There are 2 peaks: ½-1½ hrs &4-10 hrs


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Last reviewed at:
25 Nov 2019  -  1 min read




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