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Abdominal Perineal Resection - Indications, Contraindications, Preparations, and Clinical Significance

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Abdominal perineal resection extracts the anus, the rectum, and a portion of the sigmoid colon.

Medically reviewed by

Dr. Jagdish Singh

Published At December 15, 2022
Reviewed AtApril 18, 2023

Introduction:

Abdominoperineal resection primarily treats lower-positioned rectal cancer by clearing the sigmoid colon, rectum, and anus without performing a permanent colostomy. The method was foremost explained by Sir William Ernest Miles in 1908, created from more premature operations, which resulted in complications like sphincter dysfunction. Till the year the 1930s, the surgeries were executed as a two-stage operation, which involved an initial laparotomy which is done to organize the sigmoid colon and create an end colostomy.

An incision tracks this in the perineum to extract the sigmoid distal portion and rectum. In the case of low-positioned rectal cancer, traditional abdominal perineal resection is a non-standardized method related to inferior outcomes than the front area resection, which involves an increased chance of puncture, and extraction involves margin too. The planes are not explained much when assessed anatomically in the traditional procedure and include slight radical perineal dissection.

An extralevator abdominoperineal excision is a recent approach that extracts the pelvis's whole floor by further examining the extra levator muscles, highlighting detailed anatomy and radiation resection. Studies show that extralevator abdominoperineal excision reduces the chances of circumferential favorable resection boundaries as approximated with conventional abdominal perineal resection. In addition, expansive resection of the pelvis floor advances the occurrence of wound difficulties and disorders in urogenital functions. As a result of reduced repetition locally and enhanced survival, extralevator abdominoperineal excision is currently used as the best procedure in low rectal cancers.

What Is Abdominal Perineal Resection?

Abdominal perineal is a procedure for managing anal cancer and rectal cancer. In this procedure, they will remove the inferior portion of the colon, rectum, and anus to extract cancer. Abdominoperineal resection extracts the colon distally, rectum, and anal sphincter utilizing the front area of the abdominal and perineal incisions, resulting in a permanent colostomy.

It stays a significant device in the therapy of rectal cancer despite advancements in sphincter-sparing techniques. Abdominoperineal resection, for considerable years, was the therapy option for most patients with rectal cancer. Current advancements in surgical procedures and therapy may lead to significant growth in the speed of sphincter-sparing surgeries, with a simultaneous reduction in abdominoperineal resection. Thus, it is essential in a few patients, especially in distal tumors or with insufficient sphincter functioning.

What Are the Indications of Abdominal Perineal Resection?

This procedure is indicated in people with inferior rectal cancer; certain criteria are considered for selecting patients. It includes those who have an anal verge dimension of five centimeters. Also, it is not feasible to obtain an adverse margin distally. This procedure is also indicated in patients with an incursion of regional structures like an external sphincter. On average, forty percent of patients with cancer in the rectum need to be surgically treated as a component of their management. The least standard symptoms include bowel disease, which is inflammatory, and incontinence in the fecal area. Patients who cannot undergo sphincter-sparing surgery are indicated for abdominal perineal resection.

What Are the Contraindications of Abdominal Perineal Resection?

This procedure is contraindicated in those who are not regarded as appropriate for the administration of general anesthesia. Comparative contraindications include those who would not have postoperative better results, like patients with systemic diseases like inadequately maintained diabetes, dreadful obesity, deficiency, weakness, and immunosuppression.

How to Prepare for an Abdominal Perineal Resection?

A pre-operative thorough assessment should be done on each patient. Certain medical tests are done, like complete blood count, urea test and test for electrolytes, liver process tests, and imaging tests like an electrocardiogram.

Additional tests, including spirometry and transthoracic echocardiogram, were also executed to examine the status of the cardiovascular system and respiratory systems in elevated-risk patients. In addition, they are cautioned about the probable risks in the clinic, like sexual dysfunction and established pelvic aches. The stoma nurse also assesses the patient before the operation to examine the usefulness of stoma care and observe them for an appropriate site of stoma, regarding the body morphology of the patient, their lifestyle, and choices.

Patient preparation is done as follows:

  • The doctor will note the location of the colostomy if this step is not done before the procedure. The definitive location is in the iliac fossa on the left side, evading the scar tissue, folds of the abdomen,

  • Preoperative antibiotics are given parenterally.

  • The patient was seated in the modified lithotomy position utilizing stirrups in general anesthesia. The sacrum is buffered to bypass a pressure point, and the coccyx is placed at the operational table. Then a urethral catheter is placed into it to unwind the urinary sac and assess the output at the time of the function.

  • An examination is done digitally. This is done to identify the location of the disease and compare it with the anal verge.

What Are the Complications of Abdominal Perineal Resection?

The complication of abdominal perineal resection includes abdominal, perineal, and other complications.

  • Abdominal Complications - Include abscess in the intra-abdominal region, bowel obstacles, and stoma complications. These obstacles are ischemia, prolapse, etc.

  • Perineal Complications - Include delayed healing, infection, and collections in the pelvis.

  • Other Complications - Include bleeding and malfunctioning in the urinary system and sexual system.

What Is the Clinical Significance of Abdominal Perineal Resection?

It is a significant surgery that mandates considerable work-up investigator plans and caring post-operatively. This includes considerable group partners, from surgeons to anesthesiologists to experts, nurses, dietitians, therapists, and assistants. Retrieval from this process carries stability, duration, and action. Knowledge of procedure measures and possible difficulties permits them to organize for the surgery and identify the problems early. Thus all these measures lead to a positive outcome. Likewise, a preference for the available process concerning the supervision of these patients will help nurses reduce the complications and thus provide support to patients preoperatively and post-operatively.

Conclusion:

Multiple collaboration in various departments is required for better abdominoperineal resection outcomes. Pre-operative and operative planning and treatment of cancer need a multidisciplinary process. Cancer nurses and stoma nurses have an important role in the total process. Also, better retrieval has enhanced results by normalizing consideration post-operatively.

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Dr. Jagdish Singh
Dr. Jagdish Singh

Medical Gastroenterology

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