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Urethrogram - Indications, Contraindications, and Procedure

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Urethrogram is a diagnostic or imaging test recommended for males with urethral injuries. This article describes in detail about urethrogram.

Published At February 21, 2023
Reviewed AtDecember 29, 2023

What Is a Urethrogram?

A urethrogram or a retrograde urethrogram is performed most commonly in males to diagnose the problems of the urethra and urethral pathologies, including trauma and urethral strictures (narrowing of the urethra). Urethrogram allows the doctor to detect the location of the stricture, which most commonly occurs due to trauma, prolonged catheterization, surgery, and radiation therapy. Males having difficulties in passing urine and are not diagnosed with prostatomegaly or benign prostatic hyperplasia are the best candidates for this procedure. However, this procedure can only be done after a urologist has referred the patient. Urethrogram or urethrography is a contrast study mainly done under fluoroscopic control. It is a simple procedure for placing a catheter into the urethral opening. The balloon at one end of the catheter is inflated to form a seal. Then, a small amount of contrast material is injected into the urethra with the help of a catheter. Sometimes, the patient might be asked to urinate after the procedure for the voiding study.

What Are the Indications of a Urethrogram?

Urethrogram is a simple procedure usually done at the doctor’s office. However, it is specifically indicated under the following situations:

  • Trauma - Trauma is the most common indication of urethrogram. This is because the blood in the urethral opening due to blunt or penetrating trauma can cause difficulty passing urine. People with blood in the urine due to penile fracture are more likely to undergo a urethrogram. One of the most important relative indications of a urethrogram is to detect the floating prostate. Normally, the prostate gland remains firm when the doctor performs the digital rectal examination. However, the problem arises when the prostate gland is mobile, leading to urethral anomalies. Therefore, a urethrogram is done to diagnose the exact cause of urethral injuries.

  • Lower Urinary Tract Problems - Patients with a medical history of urethral stricture, urinary urgency symptoms, and incomplete bladder emptying.

  • Postoperative Evaluation - Urethrogram is commonly performed after a urethroplasty and other surgical procedures to evaluate the condition of the urethra.

What Are the Contraindications of Urethrogram?

Studies report that there are no absolute contraindications of urethrogram. As the contrast material is not injected intravenously, the risk of infection or systemic reaction is negligible. However, patients with a medical history of severe or moderate contrast reaction must be premedicated, or an alternative contrast medium must be used. People suffering from severe urinary tract infections must be treated immediately before performing a urethrogram. Sometimes, the doctor might recommend the patient be premedicated with steroids, histamine-1 blockers, or histamine-2 blockers to reduce the chances of allergic reactions. Some patients might feel embarrassed due to the procedure and might be unwilling to undergo the same. However, this feeling can be overcome by providing a piece of thorough and accurate information about the procedure.

How Is the Urethrogram Performed?

Urethrogram is a simple procedure that can be performed without anesthesia. The local anesthetic Lidocaine can be directly instilled into the urethra before the procedure, but that is not preferred nowadays. This is because the anesthetic gel would enter the urethral mucosa in case of disruption. In addition, if the patient suffers from urethral stricture, the anesthetic gel might complicate the instrumentation procedure. Therefore, the following pieces of equipment are generally used in the procedure:

  • Radiopaque contrast material.

  • A fluoroscopic X-ray machine.

  • Foley catheter.

  • Catheter tip syringe.

  • 5 mL syringe to fill the balloon attached to the catheter.

The patient is asked to lie on his back with his legs flexed at 90 degrees. The catheter is inserted into the patient’s urethra. Radioactive material is injected through the catheter into the urethra. Before the insertion of the catheter, the urethral opening and the penile foreskin are cleaned with an antiseptic. The balloon is filled with saline solution or radioactive material when the catheter is inserted in a suitable position. The urethra must not be overfilled as the urethra might rupture. The doctor obtains X-ray images as the urethra gets filled with the contrast medium. The patient must try to remain stable throughout the procedure so the doctor can obtain the static images.

What Are the Complications or Adverse Effects of the Urethrogram?

Though complications rarely occur after a urethrogram, the patient might have mild or minor hematuria (blood in the urine) after the catheter is inserted. However, this problem occurs rarely and for a short duration. After the procedure, patients suffering from urinary tract infections must be warned and asked to undergo proper investigation and treatment. If the patient suffers from an acute urethral injury, urethrography must be avoided as it might cause severe urinary retention, swelling, or edema.

What Other Imaging Procedures Can Be Used as an Alternative to Urethrogram?

Several procedures can be used as an alternative to urethrogram. Some of them are listed below:

  • CT (Computed Tomography) Scan - A CT scan is an effective procedure that helps diagnose the problems of the urethra and can be done easily at the doctor’s office. The main advantage of this procedure is that it does not require any injection of the contrast medium. Instead, the patient is simply laid on a table that goes into a device where the X-rays are taken. These X-rays are effective diagnostic aids because they allow the doctor to get three-dimensional access to the urologic system, including the urethra.

  • MRI (Magnetic Resonance Imaging) - It is similar to a CT scan, the only difference being it uses a magnetic field and radio waves simultaneously to produce the images of the urologic system.

  • Ultrasound - Ultrasound is a widely recommended procedure for obtaining images of the urethra because it is safe for pregnant females and children. However, it might not produce as clear images as the CT scan and the MRI scan. It is a simple procedure wherein the doctor first applies a gel to the patient’s stomach and moves the tip of the transducer over the gel. The sound waves from the transducer bounce back and produce images on the monitor.

Conclusion:

Urethrogram is an effective and widely used procedure to diagnose urethral problems, including urethral strictures and ruptured urethra. Though other alternative procedures are available, urethrogram is commonly preferred due to its simplicity and minimal invasiveness. Therefore, patients suffering from urethral problems must consult a urologist to learn more about the urethrogram procedure.

Frequently Asked Questions

1.

How Is a Urethrography Test Performed?

A urethrography test, or urethrogram, is the study of the urethra with the help of contrast material. This procedure is done by inserting the catheter into the urethra, a contrast material flows through it, and the balloon is expanded with the help of a saline solution. Then, the images are captured with the help of an X-ray.

2.

Is the Urethrogram Procedure Painful?

Yes, the urethrogram procedure is a little painful and might cause discomfort while inserting the catheter. The patient may also feel pressure in the urethra when the contrast material flows, especially in the case of a narrow urethra. For up to 48 hours, blood may be in the urine, and there may be a burning sensation while passing it.

3.

How Much Does a Urethrogram Test Cost?

In India, a urethrogram test and X-ray can cost around 1,200 INR to 3,000 INR. With an average cost of 1,500 INR. 

4.

What Are the Different Types of Urethrograms?

The different types of urethrograms include the study of the anterior or front part of the urethra, referred to as retrograde urethrography or ascending urethrography. When the further back part of the urethra is studied, it is called descending urethrography or micturating urethrography. When the lower urinary tract of the urethra is studied, it is referred to as voiding cystourethrography.

5.

What Are the Complications of Urethrogram?

The urethrogram procedure can cause rare complications such as hematuria (bloody urine), which occurs due to the insertion of the catheter, but this disappears within 48 hours. Other complications include damage to the urethra, disruption of the urethra, urinary tract infection, allergy to the contrast material,  and bladder perforation. Sometimes it can also cause urinary retention due to swelling of the urethra.

6.

How Long Does a Procedure of Urethrogram Take?

The urethrogram procedure, from inserting the catheter inside the urethra, inflating it, and passing a contrast material to obtaining the images with the help of an X-ray, can last for 30 to 60 minutes. It can take a little longer if the patient is more uncomfortable while inserting the catheter.

7.

How Should a Patient Be Prepared Before Undergoing a Urethrogram?

There are no restrictions on eating or drinking before the procedure, and there is no need to stop any medications. Before the start of the procedure, the penile foreskin and the urethral opening are cleaned with the help of an antiseptic solution. 

8.

What Appliances Are Used for Urethrogram?

The appliances or equipment used in a urethrogram are a Foley catheter, a thin, flexible tube passed into the urethra, and a catheter tip syringe for flowing the contrast material. A fluoroscopic X-ray machine to capture images of the urethra.  A syringe of 5 ml is also used to inflate the balloon with saline.

9.

How Is Urethrogram Different from Cystoscopy?

Cystoscopy is a type of endoscopy that is used to examine the urinary bladder and to treat urinary tract infections, bladder control issues, and bladder cancer. Whereas the urethrogram is the examination of the urethra to examine the trauma or narrowing of the urethra.

10.

Is Urethroplasty Considered Major Surgery?

Yes, urethroplasty is considered a major surgery in which the urethra is reconstructed along with its surrounding tissues. This is indicated in the case of a narrow urethra due to infection, damage, or stones. It is also indicated in the urethral diverticula (formation of sac in the urethra) and hypospadias (a birth defect where the urethral opening is not present on the tip of the penis).

11.

How Does the Retrograde Urethrogram Procedure Work?

In a retrograde urethrogram, the catheter is inserted into the urethra and the contrast material flows. With the help of an X-ray, the flow of contrast material can be seen, which passes from the urethra to the urinary bladder. 

12.

What Happens When Undergoing a Urethrogram Procedure?

There can be slight discomfort when the catheter is inserted into the urethra. The patient may feel a sensation of pressure while inserting it. After the completion of the procedure, the tip of the penis may sting for a little while. There can be blood in the urine for up to two days.

13.

What Is Urogram Used For?

Urogram is a type of test that is used to study the urinary system, which includes the ureters, kidneys, and urinary bladder. The images are then captured with the help of a CT (computed tomography) scan. During this procedure, a contrast material is injected into the vein, which flows through the urinary system and helps better outline the structures.
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Dr. Samer Sameer Juma Ali Altawil
Dr. Samer Sameer Juma Ali Altawil

Urology

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