What Does the Word Agnosia Mean?
Agnosia, which means "not knowing" in Greek, is a neurological disorder in which a patient is unable to recognize and identify things, people, or sounds using one or more of their senses, despite the fact that their senses are otherwise normal.
What Is Agnosia?
Agnosia is a relatively unusual condition in which you lose your capacity to recognize items or individuals. Agnosia is frequently caused by injury or harm to certain areas of the brain. Since it only impacts one information pathway usually, you may still be able to think normally with other areas of the brain. Although visual agnosia is the most frequent type of illness, it can impact the recognition of stimuli in any sensory modality, including visual, auditory, and tactile.
Lissauer, a German neurologist, was the first to describe agnosia in 1980, hypothesizing that object recognition occurs on two levels of processing. The first is the perceptual level, where elementary sensory data is integrated into complex forms, and the second is the associative level, where there is a comparison between what is perceived and what knowledge is stored in the memory. The impairments, however, are not attributable to a loss of memory.
What Causes Agnosia?
When a brain injury occurs along with circuits that connect primary sensory processing centers, agnosia develops. The posterior parietal cortex and the occipitotemporal regions are these centers.
It can happen as a result of:
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Ischemic Stroke- When a blood vessel supplying blood to your brain is obstructed, this form of stroke occurs.
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Brain Tumor- In the brain, when there is a cluster of abnormal cells, cancerous and non-cancerous tumors are possible. Even non-cancerous tumors can negatively impact the functionality of the brain.
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Traumatic Brain Injury- This happens when your brain is damaged by a strong hit or blow to the head. When something pierces your skull and enters your brain tissue, traumatic brain damage occurs.
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Parkinson's Disease- Parkinson's disease dementia caused due to abnormal protein accumulation in the brain can also lead to agnosia.
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Alzheimer's Disease- Alzheimer's disease is a progressive brain illness that worsens with time. It affects your brain cells by causing an abnormal build-up of protein in your brain.
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Brain Abscess- This is a pus-filled pocket in your brain. A bacterial or fungal infection is to blame. Abscesses can form as a result of injury, infection, or surgery.
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Developmental Anomalies- A developmental abnormality is a broad word that refers to problems that are present during intrauterine development or develop before the baby is born. Poisoning from carbon monoxide can also result in agnosia.
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Neurological Disease- Nervous system disorders can also cause agnosia.
To analyze something with our brain, we must first have sensory stimuli (vision, hearing, taste, touch, and smell). Our afferent or sensory route then transports these sensory stimuli to our sensory cortex. Percepts gain significance when they are processed by higher-order centers, and information becomes multimodal. Perceptual processing is required to determine what is being perceived through multiple sensory modalities, providing access to semantic knowledge and, as a result, a comprehension of the environment. Knowledge of facts, concepts, and language is preserved in semantic memory without corresponding information about the initial learning experience.
What Are the Types of Agnosia?
Agnosia can manifest in a variety of ways depending on the location of the damage. It could affect any of your senses. However, in most cases, just one sense is engaged. Some types of agnosia result in very distinct and intricate symptoms that only affect one sense.
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Auditory Agnosia: It is a condition in which a person is unable to hear. This has an effect on your hearing. If you have this sort of agnosia, you might not recognize a sound like a telephone ringing. You can, however, hear it.
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Olfactory Agnosia: It is a condition in which a person is unable to detect odors. This has an impact on your perception of a smell. You can still detect odors. You simply cannot seem to remember what you are smelling.
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Gustatory Agnosia: It has an impact on your sense of taste. When you taste anything, you do not recognize it.
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Somatosensory Agnosia: It is a type of agnosia that affects the sense of touch. This is a type of agnosia that inhibits your ability to feel touch. You can not recognize a familiar object, such as a key, without looking at it. It is easy to detect when you look at it.
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Prosopagnosia: Face blindness is another name for this condition. You may have problems recognizing familiar faces if you have prosopagnosia. Symptoms of prosopagnosia can also be more severe. They may make it difficult for you to distinguish between familiar and new faces. In severe circumstances, you may not be able to distinguish a face from an object or recognize your face.
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Visual Agnosia: It is a condition in which the ability to recognize visually presented items is impaired while having an otherwise normal visual field, acuity, color vision, brightness discrimination, language, and memory. Other sensory modalities can help patients recognize objects.
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Environmental Agnosia: It is a condition in which a person is unaware of their surroundings. This is the inability to recognize areas that are known to you, such as your house or neighborhood.
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Achromatopsia: It is also called color blindness, and it can be partial or full.
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Simultanagnosia: It is a condition in which, at any given time, you cannot see more than one thing or part of an object. You might only see the spoon if you look at a table with a plate, glass, and spoon on it. You could notice the glass but not the spoon if someone points it out.
How Is Agnosia Diagnosed?
When it comes to diagnosing agnosia, the background medical history is crucial. A thorough interview with the patient, family members, and carers aids in the identification of the etiology as well as problems with everyday activities. Simultagnosia patients, for example, have difficulty reading, writing, and understanding many items at the same time. Because diagnosing agnosia entails ruling out other possibilities, a complete neurological examination is required.
A more thorough neurologic examination is performed to detect primary abnormalities in specific senses or communication abilities that may interfere with agnosias testing. Patients may not be able to detect an object if their light touch is impaired, even if their cerebral function is normal. Only aphasia, widespread dementia, delirium, or any other deficiency that may impede some or all of the information-processing phases involved in object identification can be identified as agnosia. Aphasias might also make it difficult for the sufferer to communicate.
Neuropsychological testing could aid in the detection of more modest agnosias. It is a type of standardized testing that determines the structural and functional integrity of the brain. Intelligence, executive function (for example, planning, abstraction, and conceptualization), attention, language, perception, memory, sensorimotor functions, mood and emotion, motivation, quality of life, and personality are all evaluated. To describe a central lesion (for example- infarct, hemorrhage, or tumor) and check for atrophy suggesting a degenerative condition, brain imaging (for example- computed tomography or magnetic resonance imaging with or without angiographic protocols) is required.
How Is Agnosia Treated?
When possible, the cause of agnosia is addressed (for example- for a cerebral abscess, surgery or antibiotics, and for a brain tumor, surgery, or radiation). Patients can learn to compensate for their deficiencies with the help of speech or occupational therapists.
Agnosia does not have a specific treatment. If possible, the underlying cause will be addressed. One can learn to adjust to one’s agnosia through speech and occupational therapy. They may also be able to assist you in improving your communication skills, task planning, issue solving, and interpersonal interactions.
Conclusion:
A small percentage of agnosic patients regain sensory function, and most improvements happen during the first few months or years after diagnosis. Hence, supplementary treatment modalities play a huge role in improvement.