HomeHealth articlesvenous disordersHow Venous Thromboembolism in Hip or Knee Can Be Prevented?

Prevention of Venous Thromboembolism in Hip or Knee Replacement

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Prevention of clot formation with proper protocols is important while performing a hip or knee surgery, as it might result in venous thromboembolism.

Medically reviewed by

Dr. Ranvir Sachin Tukaram

Published At April 28, 2023
Reviewed AtMay 2, 2023

Introduction:

Hip and knee replacement surgeries are one of the most commonly performed surgeries around the globe. It is done to improve a person's walk and function and is considered one of the most life-changing surgeries. However, there is always a chance of dislodgement of clots or clotting fragments released into the system when removing the soft tissues or smoothing the bony part, which further induces thromboembolism. Thromboembolism is the obstruction of a blood vessel by a blood clot dislodged from another site of the body. Venous thromboembolism is a clinical condition characterized by blood clots in the veins, which can result in serious complications when left undiagnosed.

How Commonly Does Venous Thromboembolism Occur?

Venous thromboembolism is a common complication while performing a hip and knee arthroplasty. The incidence of venous thromboembolism is around 1.5 percent of patients even after following the prophylactic drug within three months of the postoperative period.

What Are the Methods of Preventing Venous Thromboembolism?

The doctors and the surgical team take a lot of care in preventing the dislodgement of an embolism from occluding the blood vessels. Various methods reduce the risk of ventricular thromboembolism, but the concern for potential bleeding is always a possibility. Various cautions and measures are taken to achieve this, and they are:

  • General Medical Management: The first line of management is achieved by putting the patients on medications. These are steps done while operating on the patient. The injured part is removed as quickly as possible with care followed by full surgical procedures and establishing adequate hydration during surgery.

  • Mechanical Management: This is a non-surgical way of preventing ventricular thromboembolism. Patients are asked to wear a compression stocking, while for patients undergoing complete knee arthroplasty (it is the procedure in which the worn-out knee cartilages are trimmed), mechanical foot or calf compressors provide easy backflow of the blood and prevent dislodgement of the clot. However, these compressors can be expensive, making it difficult for patients to afford them.

  • Choice of Anesthesia: The choice of anesthesia used while performing the procedure can also affect the thrombus. The anesthesia generally preferred is neuraxial anesthesia, which is preferred to be given using a spinal or epidural catheter to reduce nerve bleeding, especially when an anti-clotting medication is given side by side. It is important to follow the timing and dosage guidelines for anesthesia.

  • Anti-Blood Clotting Medications: Anti-blood-clotting medicines act on the blood, thinning it out and reducing the blood pressure preventing the clotting of blood.

  • Older Medications: The older blood clotting medicines that were widely used are Aspirin and Warfarin. But these drugs had certain drawbacks, like Aspirin being a weak clotting agent while Warfarin needs regular monitoring, is expensive, and is very time-consuming to show the effect.

  • Newer Medications: With the emergence of developing medicine, newer blood clotting drugs are preferred. These drugs have the benefit of administering both orally and intravenously. Although these drugs are essential, there is no direct comparison between the older and newer drugs.

  • Injectable Medications: Heparin is the preferred drug of choice and is used as an injectable anti-clotting medication.

How Is Venous Thromboembolism Surgically Managed?

Venous thromboembolism is surgically managed by treating the patient with a less strenuous and minimally invasive procedure. Surgical management is done by minimally invasive and less traumatic techniques. These minimally invasive surgical procedures include laparoscopy or arthroscopy, where a fiber-optic camera is inserted by making a small lesion and is operated by micro instruments controlled by the surgeon externally with the help of camera visuals, where the tissue tear is less, which in turn causes fewer fragments of the blood clot that prevent occlusion in the blood vessels.

What Are the Guidelines to Be Followed to Prevent Venous Thromboembolism?

A diagnostic workup is made before treating the patients when venous thromboembolism is suspected, as per the prophylaxis guidelines given by the American Academy of Orthopedic Surgeons.

The use of Aspirin is avoided before the surgery. The use of anti-clotting medications or compression bands is generally advised after surgery. However, those with a higher risk of thromboembolism should use both chemical and mechanical methods, whereas patients with a higher risk of bleeding are put on mechanical compressions.

The other clinical guidelines provided by the European Society are:

  • A balanced treatment approach is to be followed. This is done by proper clinical assessment, treatment plan, and discussing the cost value.

  • Choosing the correct combination of treatment: Both mechanical and chemical treatments are provided, but a correct knowledge of the treatment and to whom it is used should be considered.

How Is a Venous Thromboembolism Diagnosed?

Venous thromboembolism can be diagnosed by the following methods:

Duplex Ultrasonography: The most common method for diagnosing an embolism is through a procedure called duplex ultrasonography. Duplex ultrasonography is a method of imaging technique used to test the movement of the blood in deep veins using sound waves. This is especially used for detecting blockages in the veins or blood clots circulating in the system.

D-dimer Blood Test: A D-dimer blood test is a type of blood test that measures the amount of blood released when a clot breaks. This test is done to measure the output of fragments broken during thromboembolism.

Contrast Venography: It is a special type of radiographic imaging where a dye is injected into the veins of the leg, in the foot, or ankle and is monitored till the circulation in the hips is completed. This is used to assess the presence of any clot or obstruction in the veins.

Magnetic Resonance Imaging (MRI): Magnetic resonance imaging is a three-dimensional test that uses magnetic waves to image soft tissues. This is an imaging technique that helps to study soft tissues using sound waves. The test provides images of clots or embolisms located in the veins.

Conclusion:

Venous thromboembolism associated with total knee arthroplasty and hip arthroplasty is a very commonly occurring condition, but with the developing improvements in medications, a significant decline in the incidence of venous thromboembolism is seen. Along with medical management, an adaptation of new surgical management methods has also played a significant role in the reduction of the rate of venous thromboembolism.

Frequently Asked Questions

1.

Who Is Most Prone to Deep Vein Thrombosis?

People with a history of blood clotting anomalies, long-term immobility from extended flights or bed rest, and specific medical conditions, like cancer, are more prone to Deep Vein Thrombosis (DVT). Smoking, obesity, and the use of birth control pills are other risk factors. It is important for people who are at risk to identify the signs and take precautions.

2.

Which Organs Are Impacted by Deep Vein Thrombosis?

The veins in the legs are the main target of Deep Vein Thrombosis (DVT), which can have serious consequences, including pulmonary embolism, which occurs if a clot gets into the lungs. Although DVT mostly affects the lower limbs, severe cases can also damage the heart and other organs, leading to consequences like right heart distress.

3.

How Can One Avoid Getting Venous Thromboembolism?

Vein Thromboembolism (VTE) can be avoided by following a regular exercise regimen, particularly during prolonged periods of immobility like long trips. Drink plenty of water, avoid smoking, and visit a doctor if you have any risk factors, such as a family or personal history of blood clots. In certain situations, compression stockings or blood thinners are advised.

4.

What Are the Major Complications of Venous Thromboembolism?

Venous Thromboembolism (VTE) can have two main side effects:


- Pulmonary embolism, which can be a life-threatening condition, and


- Post-thrombotic syndrome, which results in chronic pain and swelling of the affected limb.


- However, long-term adverse effects may also include problems with anticoagulant therapy and recurrent episodes of VTE.

5.

What Makes Someone at Greater Risk of Thromboembolism?

People with a higher risk of thromboembolism a history are those with a history of


- Blood clotting disorders.


- As a surgical complication.


- Prolonged immobility.


- Obesity.


- Smoking.


- Old age.


- Certain medical conditions like cancer.


- Pregnancy.


- Use of birth control pills.

6.

What Are the Symptoms of Venous Thromboembolism?

Symptoms of venous thromboembolism (VTE) include the following symptoms and they are:


- Leg pain.


- Tenderness.


- Swelling often in one leg.


- Shortness of breath.


- Chest pain.


- Rapid heart rate.

7.

What Is the Risk of Venous Thromboembolism Throughout a Lifetime?

Although Venous Thromboembolism (VTE) risk varies, it generally increases with age. According to mortality projections, approximately 1 in 1,000 persons is likely to develop thromboembolism, and the chances rise with age and in individuals who have specific risk factors like past surgical history, cancer, or familial history.

8.

What Is the Immediate Treatment for Venous Thromboembolism?

Anticoagulant medications, such as heparin, are often used to manage Venous Thromboembolism (VTE) to prevent the further formation of blood clots. In some cases, thrombolytic treatment may dissolve already existing clots quickly. Initial management may also involve pain relief medications and compression stockings.

9.

What Are the Complications of Venous Thromboembolism?

Pulmonary embolism is one of the potentially fatal complications of Venous Thromboembolism (VTE) when left untreated. Recurrent occurrence of VTE and post-thrombotic syndrome is characterized by severe pain and swelling in the affected limb.

10.

Which Genetic Cause Is the Most Common Reason for Thromboembolism?

A mutation in the Factor V Leiden gene is the most common genetic cause of thromboembolism. Individuals with this genetic variant are more likely to develop blood clots, especially during surgery, pregnancy, or prolonged immobilization. Individuals having a familial or personal history of thromboembolism should be screened for the Factor V Leiden mutation.

11.

Can Venous Thromboembolism Be Termed As a Heart Disease?

Venous thromboembolism (VTE) is characterized by blood clots in the veins, most commonly in the legs or pelvis. While VTE is not directly related to heart disease, it may end up in major complications like pulmonary embolism, which damages the lungs and may affect heart function. Early medical attention is critical for accurate diagnosis and treatment.

12.

What Is the Difference Between Arterial Thromboembolism and Venous Thromboembolism?

Arterial thromboembolism is the production of blood clots in arteries, which can lead to illnesses such as stroke or heart attack. Venous thromboembolism, on the other hand, occurs in veins, most frequently in the legs, and can result in deep vein thrombosis or pulmonary embolism. Both include blood clots. However, arterial thromboembolism affects high-pressure arteries, and venous thromboembolism affects lower-pressure veins. These conditions' causes, symptoms, and consequences vary, requiring separate medical treatment.

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Dr. Ranvir Sachin Tukaram
Dr. Ranvir Sachin Tukaram

Orthopedician and Traumatology

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