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Protecting Little One: Understanding Group B Streptococcus (GBS) Infection During Pregnancy

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Group B Streptococcus in pregnancy can cause harm to the mother and baby. Testing and antibiotics during labor are recommended.

Medically reviewed by

Dr. Shubadeep Debabrata Sinha

Published At August 10, 2023
Reviewed AtAugust 24, 2023

Introduction

Group B Streptococcus (GBS) is a bacteria commonly found in the digestive tract and genital area of both men and women. While GBS usually does not cause any harm, it can be dangerous to pregnant women and their babies. GBS is the leading cause of sepsis, pneumonia, and meningitis in newborns and can also cause preterm labor, stillbirth, and other complications during pregnancy. Because of the potential risks, healthcare providers often test pregnant women for GBS during pregnancy, usually between 35 and 37 weeks of gestation.

In cases where a woman tests positive for GBS, it is customary to administer antibiotics during labor in order to safeguard the newborn from potential infection. This article will discuss the prevalence of GBS in pregnancy, the potential risks to both mother and baby, how GBS is diagnosed, and the current recommendations for preventing and treating GBS infection during pregnancy.

Why Is Group B Streptococcus (GBS) A Concern During Pregnancy?

GBS is a concern during pregnancy because it can cause serious infections in newborns, including:

  1. Sepsis.

  2. Pneumonia.

  3. Meningitis.

Pregnant women who carry GBS can pass the bacteria to their babies during delivery, which can result in life-threatening complications. GBS can also cause preterm labor, stillbirth, and other complications during pregnancy.

Therefore, it is important to diagnose and treat GBS in pregnant women to reduce the risk of infection in newborns and adverse pregnancy outcomes.

What Are the Potential Risks of GBS Infection During Pregnancy for Both the Mother and Baby?

Some potential risks of GBS infection during pregnancy for both the mother and baby are:

For the Baby:

  • Sepsis (infection of the blood).

  • Pneumonia (infection in the lungs).

  • Meningitis is a condition characterized by the inflammation of the membranes encompassing the brain and spinal cord, which results from an infection.

  • Preterm birth.

  • Stillbirth.

  • Long-term disabilities, such as hearing loss or developmental delays.

For the Mother:

  • Chorioamnionitis or infection of the membranes surrounding the fetus.

  • Postpartum endometritis or infection of the lining of the uterus after delivery.

  • Urinary tract infection or UTI.

  • Bacteremia or the presence of bacteria in the blood.

How Is GBS Diagnosed in Pregnant Women?

GBS can be diagnosed in pregnant women by the following method:

  • GBS screening is usually performed between 35 and 37 weeks of pregnancy.

  • The screening involves taking a swab of the vagina and rectum to test for the presence of GBS.

  • The swab is then forwarded to a laboratory for processing, and results are usually available within a few days.

  • To minimize the chances of transmitting the bacteria to her baby, it is customary for a woman who tests positive for GBS to receive antibiotics during labor.

  • In some cases, a woman may be considered high risk for GBS even if she tests negative and she may still receive antibiotics during labor as a precaution.

The recommended treatment for GBS during pregnancy is antibiotics given during labor. Here are some points about the recommended treatment:

  • If a woman tests positive for GBS during pregnancy, she should receive antibiotics during labor to lower the risk of transmitting the bacterial infection to her baby.

  • Antibiotics are typically given through an IV (intravenous) line.

  • The antibiotic used will depends on the woman's allergy history and the local resistance patterns of GBS.

  • The antibiotics are usually started at the onset of labor or if the water breaks before labor begins.

  • If the woman is allergic to antibiotics typically used to treat GBS, alternative antibiotics may be used.

  • In rare cases, if the woman is unable to receive antibiotics during labor, her baby may need to be closely monitored after delivery for signs of GBS infection.

What Are the Current Recommendations for Preventing GBS Infection in Newborns?

The current recommendations for preventing GBS infection in newborns include the following:

  • Screening pregnant women for GBS between 35 and 37 weeks of gestation.

  • Treating women who test positive for GBS with antibiotics during labor.

  • Administering antibiotics to women in labor with unknown GBS status or high-risk factors for GBS infection.

  • Avoiding routine use of antibiotics in newborns unless they are showing signs of infection or have been born to mothers with chorioamnionitis.

  • Monitoring newborns closely for signs of GBS infection is especially important if the mother has tested positive for GBS, had a fever during labor or had a prolonged rupture of membranes.

  • Educating pregnant women about GBS and its potential risks to their babies, which include the importance of seeking medical attention for symptoms of infection.

How Does GBS Infection Impact Preterm Labor and Stillbirth During Pregnancy?

GBS infection can increase the risk of preterm labor and stillbirth during pregnancy. Here is how:

  • GBS infection can cause inflammation of the placenta and membranes surrounding the fetus, which can lead to preterm labor.

  • GBS can also directly infect the amniotic fluid and fetal tissues, which can cause preterm labor and lead to stillbirth.

  • Pregnant women who are carriers of GBS are more likely to experience premature membrane rupture, increasing the risk of preterm labor and delivery.

  • GBS infection can also cause chorioamnionitis (infection of the membranes surrounding the fetus), which can lead to preterm labor, fetal distress, and stillbirth.

  • Additionally, GBS infection can lead to sepsis and other serious infections in newborns, further increasing the risk of preterm birth and stillbirth.

Conclusion

Group B Streptococcus (GBS) infection during pregnancy is a serious concern that can cause harm to both the mother and baby. GBS can lead to life-threatening infections in newborns, such as sepsis, pneumonia, and meningitis. GBS infection can also cause preterm labor, stillbirth, and other complications during pregnancy. Therefore, screening pregnant women for GBS and providing antibiotics for women in labor who tested positive administering antibiotics during labor is a crucial preventive measure aimed at reducing the risk of GBS transmission to the baby. It is crucial that pregnant women to be aware of the potential risks associated with GBS infection and to seek medical attention promptly if they experience symptoms of infection. By following current recommendations, healthcare providers can help prevent the spread of GBS and improve outcomes for both mothers and babies. Additionally, it is important for healthcare providers to educate pregnant women about GBS and the importance of testing and treatment. Women who have previously experienced GBS disease in their newborns are at higher risk of GBS recurrence in subsequent pregnancies. who have had a positive GBS test during a previous pregnancy, or who have GBS bacteria in their urine during the current pregnancy may be at higher risk for GBS infection and should discuss their individual risk factors with their healthcare provider.

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Dr. Shubadeep Debabrata Sinha
Dr. Shubadeep Debabrata Sinha

Infectious Diseases

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