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My blood smear shows mild anisopoikilocytosis. Should I be concerned?

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Patient's Query

Hello doctor,

I am 39 years old. I got a master health checkup done last week. In the blood report, the RBC smear shows mild anisopoikilocytosis with normochromic red cells mixed with microcytic, hypochromic red cells, and no hemoparasites. I am attaching my test report. What is the treatment for this?

Answered by Dr. Goswami Parth Rajendragiri

Education:

MBBS

Professional Bio:

Dr. Goswami Parth Rajendragiri is an experienced General Physician and Pathologist with extensive years of clinical expertise. He specializes in diagnosing and managing a wide range of medical conditions while providing holistic care to patients. As a Pathologist, he is skilled in performing and interpreting laboratory investigations that aid in accurate diagnosis and treatment planning. Dr. Rajendragiri is dedicated to delivering patient-focused care with a strong emphasis on preventive medicine and overall well-being.

This doctor is not available for online consultations on the platform anymore.

Hi,

Welcome to icliniq.com.

I have gone through your test report (attachment removed to protect patient identity).

  1. Your peripheral smear showing mild microcytic RBC (red blood cells) and MCV (mean corpuscular value) are slightly low, but I do not think it needs any further workup as all other smear findings are normal.
  2. Your postprandial glucose is elevated, which is suggestive of diabetes. I suggest you start taking Metformin after consulting your doctor. Control your sugar intake.
  3. The GGT (gamma-glutamyl transpeptidase) and ALP (alkaline phosphatase) values are also high with mild SGPT (serum glutamic pyruvic transaminase) elevation. Therefore, liver conditions have to be ruled out. I suggest you get USG (ultrasonography) abdomen done. If fatty liver or gallstone is present, then you have to reduce weight.
  4. Avoid alcohol and fatty food. Do regular exercise and also get your blood pressure checked. Take care and consult your physician for examination with keeping all this in mind.
Medically reviewed by Dr. K. Shobana
Published At March 13, 2017
Reviewed At August 29, 2025

Education:

MBBS

Professional Bio:

Dr. Goswami Parth Rajendragiri is an experienced General Physician and Pathologist with extensive years of clinical expertise. He specializes in diagnosing and managing a wide range of medical conditions while providing holistic care to patients. As a Pathologist, he is skilled in performing and interpreting laboratory investigations that aid in accurate diagnosis and treatment planning. Dr. Rajendragiri is dedicated to delivering patient-focused care with a strong emphasis on preventive medicine and overall well-being.

This doctor is not available for online consultations on the platform anymore.

Education:

BDS

Professional Bio:

Dr. K. Shobana is a Dental Surgeon specializing in oral health and dental care. She is skilled in preventive dentistry and provides oral hygiene education. She can do restorative treatments such as fillings and crowns. She can handle periodontal problems such as gum diseases and periodontitis. She can do root canal treatment.

This doctor is not available for online consultations on the platform anymore.

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Education:

MBBS

Professional Bio:

Dr. Goswami Parth Rajendragiri is an experienced General Physician and Pathologist with extensive years of clinical expertise. He specializes in diagnosing and managing a wide range of medical conditions while providing holistic care to patients. As a Pathologist, he is skilled in performing and interpreting laboratory investigations that aid in accurate diagnosis and treatment planning. Dr. Rajendragiri is dedicated to delivering patient-focused care with a strong emphasis on preventive medicine and overall well-being.

This doctor is not available for online consultations on the platform anymore.

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