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Can Renflexis cause ankle swelling?

This Premium Q&A, reviewed and published, features a real conversation between an iCliniq user and a physician.

Patient's Query

Hello doctor,

I am 61 years old. I have some weird swelling on my left ankle, and I took photos of it to send to my son. He is worried it is related to a Renflexis infusion I had last week. I have had RA since I was 39.

Answered by Dr. Goswami Parth Rajendragiri

Education:

MBBS

Professional Bio:

Dr. Goswami Parth Rajendragiri is an experienced General Physician and Pathologist with extensive years of clinical expertise. He specializes in diagnosing and managing a wide range of medical conditions while providing holistic care to patients. As a Pathologist, he is skilled in performing and interpreting laboratory investigations that aid in accurate diagnosis and treatment planning. Dr. Rajendragiri is dedicated to delivering patient-focused care with a strong emphasis on preventive medicine and overall well-being.

This doctor is not available for online consultations on the platform anymore.

Hello,

Welcome to the icliniq.com.

The edema due to renflexis is an uncommon side effect. If you have leg edema, then it is advisable to investigate as follow.

1. Serum protein estimation to rule out hypoproteinemia.

2. Sgpt (serum glutamate-pyruvate transaminase) to exclude liver disease.

3. Urea, creatinine estimation to rule out kidney disease.

4. Serum TSH estimation to rule out hypothyroidism.

Echocardiography to exclude cardiac cause and finally local ankle joint X-ray if needed. If edema leg more than diuretic like Furosemide can be prescribed after consultation with your doctor. I suggest you consult nearby physician for a detailed discussion of all these. I hope I have answered your question.

Medically reviewed by Dr. Nithila. A
Published At June 12, 2019
Reviewed At November 17, 2025

Education:

MBBS

Professional Bio:

Dr. Goswami Parth Rajendragiri is an experienced General Physician and Pathologist with extensive years of clinical expertise. He specializes in diagnosing and managing a wide range of medical conditions while providing holistic care to patients. As a Pathologist, he is skilled in performing and interpreting laboratory investigations that aid in accurate diagnosis and treatment planning. Dr. Rajendragiri is dedicated to delivering patient-focused care with a strong emphasis on preventive medicine and overall well-being.

This doctor is not available for online consultations on the platform anymore.

Education:

BDS

Professional Bio:

Dr. Nithila A is a Dental Surgeon specializing in providing comprehensive oral healthcare. She focuses on preventive care, routine dental treatments, and patient education to maintain optimal oral health. Known for her compassionate and patient-centered approach, she ensures comfortable and effective dental care tailored to the individual needs of each patient.

This doctor is not available for online consultations on the platform anymore.

Same symptoms don't mean you have the same problem. Consult a doctor now!

Education:

MBBS

Professional Bio:

Dr. Goswami Parth Rajendragiri is an experienced General Physician and Pathologist with extensive years of clinical expertise. He specializes in diagnosing and managing a wide range of medical conditions while providing holistic care to patients. As a Pathologist, he is skilled in performing and interpreting laboratory investigations that aid in accurate diagnosis and treatment planning. Dr. Rajendragiri is dedicated to delivering patient-focused care with a strong emphasis on preventive medicine and overall well-being.

This doctor is not available for online consultations on the platform anymore.

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