The Zonulin level in the stool is 1500. How to lower this value fast?

Hi,

Welcome to icliniq.com.

I understand your concern.

You have rightly said that there is high inflammation in the gut as Zonulin-related proteins get raised in conditions that increase gut permeability. It commonly happens when the gut becomes inflamed. Your levels are very high. The most common cause of raised Zonulin (hepatoglobulin precursor) levels in stool co-relates with a condition named inflammatory bowel disease (IBD). To make a definite diagnosis, I suggest you need further workup like gastroscopy and colonoscopy to get the tissue biopsy for histopathology that confirms the diagnosis. You may also need a CT (computerized tomography) scan based on your endoscopic examination. Extreme fatigue is part of the disease. I would suggest you meet a gastroenterologist physically who can do all the examinations for you and manage accordingly. Let me know how I can help you further. After diagnosis, treatment will be started, and your zonulin level will come down to normal.

I hope this helps.

Hi,

Welcome back to icliniq.com.

I understand your concern.

I think you need to get a second opinion from another gastroenterologist. You need to be strong at this very moment, and I know you can do it. If you still think it is hard for you, get admitted for one day then get your colonoscopy done. As you know, if we do not make a diagnosis, it is very hard to treat on assumptions. And medication has its own list of side effects, which can not be offered before diagnosis.

I hope this helps.