Common "Elevated Fecal Zonulin" queries answered by top doctors | iCliniq

Elevated Fecal Zonulin

Elevated fecal zonulin levels indicate an increase in the production of a protein called zonulin in the intestines. Zonulin plays a role in regulating the permeability of the intestinal lining. Elevated levels of zonulin may suggest an increased intestinal barrier permeability, often referred to as "leaky gut." This condition can allow the passage of unwanted substances from the intestines into the bloodstream, which may contribute to various health issues, including gastrointestinal disorders and autoimmune diseases.

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How do I lower my zonulin level in the stool?

Query: Hi doctor,I have high inflammation in the gut. The Zonulin level in the stool is 1500. How to lower this value fast? Also, I have been feeling extremely tired for one month already. I just eradicated SIBO one month ago by taking the tablet Rifaximin. Please help.  Read Full »


Dr. Rajesh Kumar Bansari

Answer: Hi, Welcome to icliniq.com. I understand your concern. You have rightly said that there is high inflammation in the gut as Zonulin-related proteins get raised in conditions that increase gut permeability. It commonly happens when the gut becomes inflamed. Your levels are very high. The most commo...  Read Full »

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