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Am I taking right medication for GERD?

This Premium Q&A, reviewed and published, features a real conversation between an iCliniq user and a physician.

Patient's Query

Hi doctor,

I am a 50-year-old male. My weight is 158.7 lbs, and my height is 5 feet 5 inches. I am a vegetarian. I do not drink alcohol, and I do not smoke either. I have recently stopped taking tea and coffee. I do exercise regularly. I have been suffering from the following symptoms for the last five years, but not daily. There is a sudden awakening from sleep due to a feeling of suffocation, sometimes a feeling of breathlessness, even if I am awake. Sometimes, a flu-like experience passes throughout the body. This is quite evident immediately after a sexual ejaculation. My ECG, 2D echo, treadmill test, pulmonary function test, chest x-ray, and MRI brain scan were normal.

I do not feel any heartburn or acid entering the throat. For the last three months, I have been under medication for suspected GERD. My current medications are Topcid 40 mg, Nexpro 40 mg, and Perinorm CD. Especially with the last medicine, I am a little bit apprehensive as I feel uncomfortable after having it. I would like a second opinion on my symptoms, the probable causes, and the medicines prescribed.

Thank you.

Answered by Dr. Kannane Tirougnanassambandare

Hi.

Welcome to icliniq.com.

From going through the information you have provided, it is clear that currently you are on treatment for suspected GERD - gastroesophageal reflux disease (acid reflux disease). You have been having intermittent problems for over five years.

Acid reflux can cause breathlessness and waking up from sleep at night. Some might feel and describe heartburn, but others may not actually feel the burning sensation. The symptoms can be worsened by stress, anxiety ,and panic attacks.

My recommendations are that an endoscopy procedure called gastroscopy will help to check for any weakness in the valve at the lower end of the food pipe (gullet or esophagus) and to directly visualize any evidence of inflammation there which is reflux esophagitis.

Following the above test, you may require a 24-hour pH monitoring study and a manometry test to confirm that acid is refluxing back whenever you have symptoms and that there is no problem with the motility of the gullet.

I agree with you that I would not continue on Perinorm CD (Metoclopramide). I tend to give it only for nausea or vomiting.

  • Nexpro (Esomeprazole) 40 mg is best taken once daily on an empty stomach in the morning. If despite these symptoms persist, it can be taken twice daily before food, that is, before breakfast and the other before dinner at night.
  • You can take Topcid (Famotidine) 40 mg at bedtime to prevent symptoms at night.
  • Eat smaller and frequent meals. Try to eat more slowly, try to spend at least 30 minutes per meal, and avoid eating on the run.
  • Avoid large, high-fat meals. Avoid late evening snacks or eating before bed. Avoid lying flat after eating; try sitting up for at least two hours after finishing a meal and sleeping on your left side.
  • Try light walking for 15 to 30 minutes following a meal. Try chewing non-mint type chewing gum for 30 minutes following a meal.
  • Raise the head of the bed 6 to 8 inches to prevent reflux when sleeping. Extra pillows may only elevate your head. Try putting pillows under the mattress near the head of the bed or use a special wedge.
  • Avoid tight-fitting clothes around the abdomen. I wish you a speedy recovery.
  • Some people with GERD may find that eliminating certain foods helps to improve their symptoms. For example, avoiding spicy foods, raw onion, garlic, black pepper, citrus products and juices of orange, grapefruit or cranberry, tomato products, chocolate or brownies, caffeine, sodas, coffee, tea, etc., peppermint, fatty or greasy foods.

I hope this helps.

Kindly revert so I can assist you further.

Thank you.

Investigations to be done

Investigations to be done are: 1. Gastroscopy. 2. 24 hour esophageal pH monitoring and esophageal manometry.

Probable diagnosis

The probable diagnosis are: 1. GERD. 2. Functional dyspepsia.

Patient's Query

Thank you doctor,

I would like to know more about proton pump inhibitors. Kindly explain, please.

Answered by Dr. Kannane Tirougnanassambandare

Hi,

Welcome back to icliniq.com.

  • Medicines used to control acid called proton pump inhibitors are quite useful for this purpose.
  • They are also relatively safe, but as like any other medications, should be used under the guidance of the doctor as needed for the prescribed time.
  • Long-term use of any medication may have undesirable side effects and should only be done if there is a need for the drug.

Answered by

Dr. Kannane Tirougnanassambandare

Medically reviewed byDr. K. Shobana

Published At August 9, 2017
Reviewed AtJuly 24, 2025

Same symptoms don't mean you have the same problem. Consult a doctor now!

Dr. Kannane Tirougnanassambandare

Dr. Kannane Tirougnanassambandare

Medical Gastroenterology

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