HomeAnswersSurgical Gastroenterologygastrointestinal abnormalityWhat causes intestinal hyperpermeability?

Are hyperpermeable intestines treatable and curable?

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The following is an actual conversation between an iCliniq user and a doctor that has been reviewed and published as a Premium Q&A.

Medically reviewed by

Dr. Vinodhini J.

Published At February 25, 2020
Reviewed AtDecember 7, 2023

Patient's Query

Hello doctor,

Is hyperpermeable intestine treatable? Kindly suggest.

Answered by Dr. Saumya Mittal

Hi,

Welcome to icliniq.com.

I hope the following information will help you understand the condition first, and thereafter the possibility of cure and treatment. Together it should help you get your answer. To start with, I am sorry, but your question does not have a simple yes or no answer. Normally, the gastrointestinal epithelium provides a semi-permeable barrier that allows nutrients to be absorbed while preventing larger, potentially toxic, antigenic, or pathogenic molecules or organisms from crossing into the bloodstream. Abnormally increased intestinal permeability allows the individual to absorb the bad food molecules and absorption of bacteria and/or yeast from the gut to extra-intestinal sites, such as mesenteric lymph nodes, liver, spleen, and systemic circulation. This can be also be due to certain drugs, microbial overgrowth, radiation, stress, alcohol intake, enteral or parenteral nutrition, or injury. Increased intestinal permeability occurs commonly with diseases including inflammatory bowel disease, rheumatoid arthritis, ankylosing spondylitis, asthma, eczema, food allergies, alcoholism, trauma, and surgery.

Glutamine, phosphatidylcholine, flavonoids, soluble fiber, and fish oil, as well as probiotic organisms, including Lactobacilli and Saccharomyces boulardii, can assist in correcting this abnormal permeability. It would be necessary to avoid triggers like alcohol. And of course, other conditions like rheumatoid arthritis should be looked for. The treatment of cause will help remove the cause. So the treatment and cure would depend on how well one is evaluated.

Same symptoms don't mean you have the same problem. Consult a doctor now!

Dr. Saumya Mittal
Dr. Saumya Mittal

Internal Medicine

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