I am not able to walk due to leg weakness and fatigue. Is it myasthenia gravis?

Hi doctor,

I am a 17-year-old female. I have this problem for about two and a half years. I feel weak and fatigued to the point where I am not able to walk sometimes. It tends to show fluctuation for two days. It becomes fine on the next day and the weakness comes back again. I do not have enough strength to do my work. I feel tired. My legs and arms seem to be weak. I have done many tests and all the results came back normal. I have done MRI of the brain and spine, EEG, ECG, complete blood count, vitamin B12, thyroid function test, and lipid profile test. All the results came back normal. I consulted a neurologist and she advised me to do an RNS test for myasthenia gravis. Another neurologist advised me to do an anti-AChR and anti-MuSK antibody test. I have done the tests and the results came back negative. Do I need to do a repetitive nerve stimulation test further? Please suggest.

Thank you doctor,

I manage diabetes by taking Glimepiride and Glucophage. Before three years, I was asthmatic and the doctor suggested me to take Prednisolone six tablets for five days. After taking it, I noticed that I was not able to walk well and started to have high blood sugar levels. I do not had my energy to do my work and I always sleep on my bed. At one point, I was using a wheelchair for two weeks. After that, I got better. Now, I feel tired all the time. When I do some work while having a bit of energy, I become weak again. I feel difficult to get back my energy after taking a rest. Please advise.

Thank you doctor,

I do not have numbness in my legs. I am not taking steroids now. I have stopped taking it as the whole problem got started after taking it.

Thank you doctor,

I have done kidney function tests, thyroid function tests, and vitamin B12. All the results came back normal. My slippers does not slip. Most of the time, I have weakness in my legs while walking. I can walk but I fall down suddenly. Sometimes, I will be fine for several months and I have weakness again. I was fine for ten months and then again I became sick. My mood seems to be fine. I do not have any sudden anger outbursts.

Thank you doctor,

I have difficulty while lifting my arms above the shoulder. I do not feel difficult while getting up from the chair. I do not have any difficulty while getting up from the squatting position. I do not have numbness in my legs. I can walk well sometimes my knees goes down while walking. I am staggering.

Thank you doctor,

Mostly, it ranges from 90 mg/dL to 130 mg/dL.

Thank you doctor,

Yes, I can do the NCV test here.