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What is RAEB? What can it lead to?

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The following is an actual conversation between an iCliniq user and a doctor that has been reviewed and published as a Premium Q&A.

Medically reviewed by

Dr. Sneha Kannan

Published At December 10, 2015
Reviewed AtAugust 16, 2023

Patient's Query

Hi doctor,

I am writing to you regarding the health status of an elderly person. She is 85 years old and still in pretty good condition. Her current cardiological status is rated to be very well with no diabetes or any other medical issues. But from last year she shows a myelodysplastic syndrome. A bone marrow biopsy was attempted a couple of weeks ago. Unfortunately, the material made available to the laboratory was not adequate in quality and no result could be given. However, I read in the report that the material was of fibrino-leukocytic consistency and assumed that there is refractory anemia with excess blasts. Is the material of fibrino-leukocytic nature possibly proving the suspected condition?

Hi,

Welcome to icliniq.com.

I have carefully worked through your case and want to assure you that proper care and expert opinion will be extended.

When there is a hematology report which questions the quality of the biopsy specimen, we cannot just comment on the outcome of the test or what should have been there if it was like that or the other way.

The fibrino-leukocytic consistency just means that there were just a few leukocyte cells in the background matrix of fibers.

I preferably suggest that this is a mistake in taking the proper specimen, or if the technique was fine then due to the replacement of the bone marrow with fibrous tissue to some extent causing anemia. My final suggestion is to repeat the diagnostic test and expert hands needed.

Patient's Query

Hi doctor,

Thank you for the reply,

Is the use of term material fibrin-leukocytic consistency in the report not necessarily hinting the stage of possible refractory anemia with excess blasts? If the test had been done on a known healthy patient, is the same consistency of the material identified as well?

Hi,

Welcome back to icliniq.com.

I want to assure you that do not worry as everything is going to be fine soon. I have thoroughly gone through your case and can well understand your genuine concerns.

Same symptoms don't mean you have the same problem. Consult a doctor now!

Dr. Muhammad Majid Hanif
Dr. Muhammad Majid Hanif

Cardiology

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