HomeAnswersGeneral PractitionerrisperidoneIs it advised to avoid Risperidone with Tramadol?

Is it good to have Risperidone and Tramadol together?

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The following is an actual conversation between an iCliniq user and a doctor that has been reviewed and published as a Premium Q&A.

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Published At November 27, 2020
Reviewed AtJuly 10, 2023

Patient's Query

Hello doctor,

I have an urgent question and I do not know what to do. My mother in law (72 years old) who was a healthy and active person was suddenly diagnosed with Colon cancer last year. She was on chemo and radiotherapy treatment up until her last operation before 7 months where she was told she was cured. She was fine and back to her active ways yet she took it easy. Around a two months ago she had this pain in her back which kept getting worse. At first the doctor said it was just the cold got to her but it became too extreme to handle and she was referred to a neurosurgeon who said she need to operate that instant as she had some lesions on her vertebrate. She had a successful operation on two weeks ago and because of the pain they gave her Tramadol. Instantly she started hallucinating and was acting all confused. This lasted for a few days after the operation after she went back home. When her daughter contacted the doctor to say that she was hallucinating and saying weird things he prescribed her Prisdal (Risperidone). So she was taking this along with Tramadol. A few days later she stopped talking and became extremely lethargic. When her son and daughter took her to emergency they said she had anemia and gave her blood transfusion. They would not say what was wrong with her and the doctor wouldn’t answer his phone. They were fed up as no one would give them a straight answer. Her son contacted a friend who is a pharmacist. he was furious and said that it was very dangerous to take Tramadol and Risperidone together and she most likely had overdosed. Now my mother in law Is just lying in her bed and cannot move. This morning they would get a response from her by nodding and making a humming noise when they ask her a question. They have been feeding her with a syringe. We do not know what to do now. I just checked on her now and she is just lying there with her eyes closed immobile. She had a few syringe of water and some blended vegetable soup.

Hello

Welcome to icliniq.com.

I completely understand your concern regarding your mother in law’s condition. Risperidone and Tramadol have major interactions that can lead to severe health problems like depression, respiratory distress and therefore these should be avoided giving together. Her current condition needs to be assessed properly. If possible monitor her blood pressure as well as oxygen saturation if you have pulse-oximeter available at home. My advice to you is, take her to ER and get her examined as well as blood work up done there as per the doctor’s advice. Effects of the medications needs to be monitored along with proper management. There is need of oncologist consultation as well. Once she is stable she will be brought back home. Hope this helps. Feel free to contact for any further query in the future. Thank you.

Same symptoms don't mean you have the same problem. Consult a doctor now!

Dr. Manisha Raghunath Auradkar
Dr. Manisha Raghunath Auradkar

General Practitioner

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