Q. Does using Noctiva nasal spray reduce the sodium levels in the body?

Answered by
Dr. Karthik Rajan
and medically reviewed by iCliniq medical review team.
This is a premium question & answer published on Oct 20, 2018

Hi doctor,

I had a bladder leakage at night. I tested my urine. It was fine. I do not have urine leakage during the daytime. I had this problem before five months. My urologist gave me Nocitva nose spray. I have read that using Noctiva can lower the sodium present in the body. I tested my sodium level before eight months. It was 142 mEq/L. Do I need to check my sodium level now? Please suggest.



Welcome to

Yes, using Noctiva nasal spray (Desmopressin acetate) can cause a decrease in sodium levels in the blood. The risk is small, and it usually happens within the first month. Then your body starts coping with it. Generally, we measure the sodium levels just before starting the drug, a week after starting the medication and a month after taking the drug. If we find the levels in a stable condition, then we repeat them once in six months. In your case, as you have started the medication, I would advise you to get a sodium level now and a couple of weeks later. If they are normal, then you can get it done for every six months. It is just a precaution to monitor these levels, as the actual risk of developing low sodium levels is less than 10 %.

Thank you doctor,

I had checked the sodium levels before eight months. It was 142 mEq/L. Does it get changed soon?



Welcome back to

It is not possible to use the sodium levels measured before eight months. Having a recent value measured within a week is necessary. It is a highly reliable value that can change in a matter of hours. Hence it is better to do testing to know a recent value. If we find that the dosage of the medication does not cause a change in the sodium levels, or if there is no change in the sodium levels, then the sodium levels can be measured at lengthier intervals.

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