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What is the reason for high thyroglobulin antibodies?

This Premium Q&A, reviewed and published, features a real conversation between an iCliniq user and a physician.

Patient's Query

Hello doctor,

I got my blood work done, and they told me I have high thyroglobulin antibodies measured by the Beckham Coulter Methodology. My thyroid ultrasound came back normal. Why do I have this? And which doctor should I consult?

Please advise.

Thank you.

Answered by Dr. Shaikh Sadaf

Education:

MBBS

Professional Bio:

Dr. Shaikh Sadaf is a Specialist in Diabetology and Endocrinology dedicated to providing comprehensive care for patients with hormonal and metabolic disorders. With two decades of clinical experience, she is skilled in managing diabetes, thyroid conditions, and a wide range of endocrine issues. Having trained internationally and earned prestigious memberships from leading medical colleges, Dr. Sadaf combines global expertise with a compassionate, patient-centered approach. She focuses on personalized treatment, preventive care, and long-term wellness to help patients achieve better health outcomes.

This doctor is not available for online consultations on the platform anymore.

Hello,

Welcome to icliniq.com.

I read your query and your reports that you have attached (attachment removed to protect patient identity).

High thyroglobulin antibodies indicate an autoimmune thyroid disease that can occur either sooner or later, but cannot predict when it will happen exactly. Autoimmune disease means that the body’s defense mechanism, instead of attacking the bugs, starts attacking its own organs.

In your case, it is the thyroid gland. It can be Hashimoto’s thyroiditis or Graves' disease. It is not possible to predict which one. Nonetheless, you are fine, and you must take care of yourself by living a healthy life with proper sleep, good dietary habits, and some physical exercise. If you ever have low immunity due to any reason, you can develop thyroid disease, but you cannot say it for sure.

You also have some lymph nodes in the neck, but that could be due to infection in your throat or any other medical condition. But it needs to be investigated further. Regarding thyroid, you can follow up with an endocrinologist and follow up periodically for thyroid tests every three to six months to make sure you do not develop any thyroid disease that goes undetected.

I hope this helps.

Thank you.

Patient's Query

Hello doctor,

Thank you for the reply.

What should I do now? I am gaining a lot of weight. What other blood tests should I do? I feel something is wrong.

Please help.

Answered by Dr. Shaikh Sadaf

Education:

MBBS

Professional Bio:

Dr. Shaikh Sadaf is a Specialist in Diabetology and Endocrinology dedicated to providing comprehensive care for patients with hormonal and metabolic disorders. With two decades of clinical experience, she is skilled in managing diabetes, thyroid conditions, and a wide range of endocrine issues. Having trained internationally and earned prestigious memberships from leading medical colleges, Dr. Sadaf combines global expertise with a compassionate, patient-centered approach. She focuses on personalized treatment, preventive care, and long-term wellness to help patients achieve better health outcomes.

This doctor is not available for online consultations on the platform anymore.

Hello,

Welcome back to icliniq.com.

You can do a complete blood count, lipid profile, renal and liver function tests, and vitamin D levels. Regarding your weight gain, this is not due to an issue with your thyroid gland, as it is functioning normally. Try checking with a gynecologist regarding PCOS (polycystic ovary syndrome) because, if present at all, it can cause weight gain.

You can also check LH (luteinizing hormone) and FSH (follicle-stimulating hormone) hormone levels on the second day of your period.

I hope this helps.

Thank you.

Medically reviewed by Dr. Vinodhini J.
Published At November 10, 2020
Reviewed At December 17, 2025

Education:

MBBS

Professional Bio:

Dr. Shaikh Sadaf is a Specialist in Diabetology and Endocrinology dedicated to providing comprehensive care for patients with hormonal and metabolic disorders. With two decades of clinical experience, she is skilled in managing diabetes, thyroid conditions, and a wide range of endocrine issues. Having trained internationally and earned prestigious memberships from leading medical colleges, Dr. Sadaf combines global expertise with a compassionate, patient-centered approach. She focuses on personalized treatment, preventive care, and long-term wellness to help patients achieve better health outcomes.

This doctor is not available for online consultations on the platform anymore.

Education:

BDS

Professional Bio:

Dr. Vinodhini J. is a Dental Surgeon with extensive years of clinical experience. She specializes in the diagnosis, prevention, and treatment of dental and oral health issues, including restorative, surgical, and cosmetic procedures. With a patient-centered approach, she focuses on maintaining oral health, alleviating discomfort, and enhancing smiles. Her expertise ensures comprehensive care tailored to each patient’s dental needs and overall wellbeing.

This doctor is not available for online consultations on the platform anymore.

Same symptoms don't mean you have the same problem. Consult a doctor now!

Education:

MBBS

Professional Bio:

Dr. Shaikh Sadaf is a Specialist in Diabetology and Endocrinology dedicated to providing comprehensive care for patients with hormonal and metabolic disorders. With two decades of clinical experience, she is skilled in managing diabetes, thyroid conditions, and a wide range of endocrine issues. Having trained internationally and earned prestigious memberships from leading medical colleges, Dr. Sadaf combines global expertise with a compassionate, patient-centered approach. She focuses on personalized treatment, preventive care, and long-term wellness to help patients achieve better health outcomes.

This doctor is not available for online consultations on the platform anymore.

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