My wife has urticaria. Please help.

Q. My wife has urticaria. Please help.

Answered by
Dr. Sushil Kakkar
and medically reviewed by iCliniq medical review team.
This is a premium question & answer published on Aug 14, 2014 and last reviewed on: Jan 20, 2022

Hello doctor,

My wife has been getting a rash which the doctor has termed as urticaria. What could have caused this? I feel she could be having a yeast intolerance. Please help.



Welcome to

Your wife has been treated for urticaria. I would keep a possibility of idiopathic urticaria/hives.

It presents as sudden skin welts/swellings, which can be distributed all over the body. Itching is usually severe; however it is subjective in individuals.

The causes of urticaria includes various factors such as infections (bacterial, viral or fungal), drugs like painkillers and also certain foods, additives and preservatives.

Physical urticaria can occur due to cold temperature, heat, dermographism, etc., and cholinergic urticaria will occur in response to strong emotions, exercise, spicy food, etc.

Autoimmune urticaria associated usually associated with autoimmune disease such as thyroid, rheumatoid arthritis, systemic lupus erythematosus, etc.

The most common one is idiopathic urticaria, where there will be no underlying identifiable cause.

Regarding treatment, I suggest oral antihistamines like Montelukast and Levocetirizine once daily. Also she can take tablet Allegra 120 mg (Fexofenadine) once daily.

Treatment may sometimes last for months or years. A topical soothing lotion like calamine would help her symptomatically.

Kindly get the food allergy tests and thyroid tests to rule out yeast intolerance.

Revert back with the reports to a dermatologist online -->

Hello Doctor,

Thank you for your quick and explanatory reply.

We have done the thyroid tests, the results show no abnormalities. Do we have to do any other tests?



Welcome to

I guess you suspect her to be yeast intolerant and it could be the responsible cause for her urticaria.

There is no scientific proof regarding an entity called yeast intolerance.

I would rather suspect that she has Chronic Idiopathic Urticaria (CIU).

It is well-recognized that 30-40% of Chronic Idiopathic Urticaria is autoimmune in nature.

I would therefore recommend an ASST test for her (Autologous Serum Skin Testing).

This test is to either rule out or confirm Chronic Autoimmune Urticaria (CAU).

  • The Autologous Serum Skin test is used as a screening test for Chronic Autoimmune Urticaria and has a sensitivity and specificity of about 70% and 80%, respectively.
  • There is a strong link between Chronic Autoimmune Urticaria (CAU) and Autoimmune thyroid disease.
  • However, most of these patients are euthyroid (normal thyroid gland functioning) just as in case of your wife.
  • Treatment would remain the same and may sometimes need to be taken for months or years.

Revert back with the test reports to a dermatologist online -->

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