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Sitz Marker Study - Importance, Applications, Procedure, Benefits, and Risks

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A Sitz marker study is a diagnostic test used in patients suffering from chronic constipation. It is also known as a colon transit study.

Medically reviewed by

Dr. Muhammad Shoyab

Published At September 1, 2022
Reviewed AtJanuary 4, 2024

What Is a Sitz Marker Study?

A Sitz marker study is a diagnostic test for chronic constipation in adults and children. In this test, tiny radio-opaque markers are used to evaluate the function of the colon, that is, how fast or slow the food moves through the intestine. In other words, this test is used to measure the amount of time taken for the stool to pass through the colon and exit the body.

What is the procedure of Sitz Marker Study?

The Sitz marker study is a diagnostic test used to assess the transit time of the colon. In this procedure, small markers or capsules are swallowed, and their movement through the digestive system is tracked via X-rays or other imaging techniques over several days. Patients typically adhere to specific dietary guidelines and return for periodic imaging sessions to monitor the markers' progress. By analyzing the markers' location in subsequent X-rays, healthcare providers can determine the transit time through the colon, aiding in identifying potential issues with bowel movements or transit. Following completion, patients discuss the test results with their healthcare provider to understand any implications for their digestive health. Always consult with a healthcare professional for personalized guidance and interpretation of test results.

What Is the Use of X-Ray in Sitz Marker Study?

X-rays serve as a pivotal tool in the Sitz marker study by visualizing and monitoring the movement of ingested markers through the gastrointestinal tract. These markers, mimicking the passage of food through the colon, are tracked via X-ray imaging at intervals over several days. This imaging technique enables healthcare providers to observe the markers' progression, identify any areas of retention or slow movement, and determine the transit time through the colon. By assessing marker location and distribution, X-rays aid in diagnosing conditions such as slow transit constipation or motility disorders by pinpointing abnormalities or areas of stasis where markers accumulate

How to Prepare for the Sitz Marker Study Test?

Preparation for a Sitz marker study involves several steps to ensure accurate assessment of colon transit time. Following consultation with a healthcare provider, specific guidelines will be provided. This typically includes adhering to a prescribed diet, often low in fiber, for a few days before the test. It's important to stay hydrated throughout the process and follow any dietary restrictions strictly. Patients should maintain normal activity levels unless otherwise directed and record marker passage as instructed. Understanding the procedure timeline and adhering closely to healthcare provider instructions are essential for a successful and reliable Sitz marker study. Communication with the healthcare team is key to addressing any concerns and ensuring proper preparation for the test.

What Is the Importance of the Sitz Marker Study?

Irregular bowel movements and constipation are major problems affecting the majority of the population. Though some find relief with dietary changes and lifestyle medication, others may not. There might be numerous reasons for constipation to occur; hence it’s imperative to identify the cause of constipation.

The Sitz marker test is one such diagnostic test that can be helpful in identifying the reason for constipation by measuring the colon transit time. The colon is the terminal portion of the gastrointestinal tract that transports food materials from the small intestine to the rectum, where it is expelled out through the anus. With the help of this test, physicians will be able to identify if the constipation is due to abnormal colonic motility or if there are any other obstructive or structural problems involved.

Where Is Sitz Marker Study Used?

It can be used both in the adult population and in children.

Used in chronic constipation cases (less than two bowel movements per week or straining more than 75 percent).

What Are the Pre-Procedure Preparations?

No dietary changes required. The patient may continue their existing diet. Patients are advised to avoid laxatives, enemas, and suppositories during the entire test. Pediatric patients may require a bowel cleansing before the procedure if advised by the pediatrician.

How Is Sitz Marker Study Done?

  • It is a very simple test. The most commonly used procedure is the standard single-capsule Sitzmark study.

  • The first step is to swallow the Sitz marker capsule. These are gelatin capsules, each containing 24 tiny ring-like radiopaque markers.

  • In pediatric patients, the capsule may be broken, and the radiopaque markers may be mixed with food.

  • The child must not chew these markers and need to swallow them as a whole.

  • It should be ensured that they swallow all the rings.

  • An abdominal X-ray should be taken exactly five days after ingesting the capsule.

  • Some physicians may advise a modified procedure that involves taking one capsule every day for four days and then the X-ray to be conducted on the 5th or 7th day.

What Are the Instructions After Procedure?

The patient may resume their normal activities and diet. Patients should avoid laxatives or any form of enema till the abdominal X-rays are taken.

How Is the Result Interpreted?

  • The Sitz marker capsules contain tiny radiopaque markers, which can be seen on X-rays, thus helping the doctors to trace their movement through the intestine, to see if they are expelled completely or partially, and also the time taken for them to be expelled.

  • If over 80 percent of markers are expelled, then the colonic transit has no significant abnormality.

  • If the markers are found scattered evenly throughout the colon, it is suggestive of hypomotility; that is, the contents are moving slowly through the gut. It is also known as slow transit constipation.

  • If the markers have progressed through the proximal colon but are found stagnating in the rectum, indicative of obstructive constipation or outlet delay.

What Are the Benefits of This Study?

  • Reliable and reproducible.

  • Easy to perform and painless.

  • Cost-effective.

  • Can determine the severity of the problem and also monitor the response to treatment.

What Are the Risks Associated With This Study?

  • Risk of radiation exposure.

  • To be avoided in pregnant women and lactating mothers.

  • Risk of choking on the capsule in pediatric patients; hence children need to be supervised by adults while consuming these capsules.

  • Hypersensitivity reaction to the components of capsules.

Conclusion:

Constipation is a major medical issue affecting a huge number of people. Chronic constipation can cause stress, anxiety, and depression, thereby resulting in poor quality of life. It is usually a manageable and preventable condition, provided the cause is known. Various tests are available to determine the cause of constipation. Sitz marker study is one such used in chronic constipation cases. Based on the results of the test, physicians will be able to advise the treatment modality. Slow transit constipation patients could benefit from dietary changes, lifestyle modification, or prokinetics, whereas obstructive constipation may require laxatives or a surgical approach. Thus, prompt diagnosis and appropriate treatment could help patients improve their quality of life to a great exten

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Dr. Muhammad Shoyab
Dr. Muhammad Shoyab

Radiodiagnosis

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