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Traveler’s Diarrhea - An Overview

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The most foreseeable sickness associated with travel is travelers' diarrhea (TD). Read below to learn more about travelers' diarrhea.

Medically reviewed by

Dr. Nagaraj

Published At June 22, 2023
Reviewed AtMarch 28, 2024

Introduction

Traveler's diarrhea is a digestive system condition that frequently results in loose stools and discomfort in the abdomen. It is brought on by ingesting contaminated food or water. Fortunately, traveler's diarrhea commonly causes unpleasant symptoms in most people and is not dangerous. People run a higher risk of getting traveler's diarrhea if they go somewhere where the weather or sanitary standards differ from those at home. People should be cautious about the food and beverages they consume while traveling to lower their risk of developing traveler's diarrhea. If they do have traveler's diarrhea, it probably will go away on its own. If diarrhea persists or worsens, it is a good idea to have doctor-approved drugs when anyone travels to high-risk areas.

Several intestinal infections can cause TD, a clinical condition. The main danger is bacterial infections, which are considered to be responsible for 80 % to 90 % of TD. Although multiplex molecular diagnostic assays improve their detection, intestinal viruses may be responsible for at least 5 % to 15 % of infections. Protozoal infections, which jointly account for 10 % of diagnoses in longer-term travelers, take longer to present symptoms. Consuming poisons that have already been generated in food results in what is referred to as "food poisoning." Vomiting and diarrhea are both possible symptoms of this condition, but they typically go away on their own within a day.

Which Infectious Agents Are the Cause of Traveler's Diarrhea?

The most common cause of TD is bacteria. Overall, enterotoxigenic Escherichia coli is the most often found pathogen, followed by Campylobacter jejuni, Shigella spp., and Salmonella spp. In cases of TD, enteroaggregative and other E. coli pathotypes are frequently discovered. As probable causes of TD, there is also growing discussion of Aeromonas species, Plesiomonas species, and recently identified pathogens (Acrobacter, Larobacter, enterotoxigenic Bacteroides fragilis). Numerous pathogens, such as norovirus, rotavirus, and astrovirus, can cause viral diarrhea.

The most common protozoal pathogen detected in TD is giardia. In addition to Cryptosporidium, Entamoeba histolytica is a relatively uncommon cause of TD. The most well-known risk areas for Cyclospora include Nepal, Peru, Haiti, and Guatemala. The risk is largely geographical and seasonal. A Flagellate called Dientamoeba fragilis is occasionally linked to traveler's diarrhea.

What Are the Associated Risks for Traveler's?

TD affects both men and women equally, and it affects young adults more frequently than it does older travelers. More than one episode of TD may happen during a single journey, and in short-term travelers, TD assaults do not seem to shield against subsequent ones. In their first year, a group of expats living in Kathmandu, Nepal, had an average of 2 to 3 episodes per person. Seasonal fluctuations in the risk of diarrhea may occur in more temperate areas. For instance, in South Asia, rates of TD attacks spike during the hot months before the monsoon.

The amount of stool pollution in the environment will be larger and more accessible to flies in warmer areas where many people lack access to plumbing or latrines. Insufficient electrical power may cause frequent blackouts or improperly working refrigeration, which could result in unsafe food storage and a higher risk of illness. Lack of clean water can cause meals and beverages made with it to be contaminated, and a lack of it can make it easier to skip steps when washing hands, surfaces, utensils, and even products like fruits and vegetables. Additionally, there could not be any handwashing facilities in the regions where food is prepared because doing so might not be a social custom and might be expensive. It has been shown that the risk of TD decreases in locations where appropriate food management courses have been offered. However, germs like Shigella sonnei have led to TD connected to the handling and preparation of food in restaurants, even in industrialized nations.

What Are the Signs and Symptoms of Traveler's Diarrhea?

Both bacterial and viral TD manifest with the abrupt onset of unwelcome symptoms ranging from minor cramps and urgent loose stools to severe abdominal discomfort, fever, vomiting, and bloody diarrhea, but vomiting may be more noticeable in norovirus cases. Typically, protozoal diarrhea, such as that brought on by Giardia intestinalis or E. histolytica, begins more gradually and manifests as 2–5 loose stools daily. A hint of the etiology can be found in the incubation interval between exposure and clinical presentation:

  • Symptoms from bacterial toxins typically appear within a few hours.

  • The incubation period for bacterial and viral infections is 6–72 hours.

  • Protozoal pathogens rarely exist during the first few days of travel and often have an incubation period of 1-2 weeks. Cyclospora cayetanensis is an outlier because it can appear quickly in high-risk locations.

Bacterial diarrhea often lasts 3 to 7 days without treatment. Usually, viral diarrhea lasts two to three days. Without treatment, protozoal diarrhea can last for weeks or months. Even in the absence of ongoing infection, an acute episode of gastroenteritis might result in lingering gastrointestinal symptoms. Post-infectious IBS is the term used to describe this presenting symptom. Reactive arthritis and Guillain-Barré syndrome are two other post-infectious after effects.

How to Prevent the Signs of Traveler's Diarrhea?

Several strategies can lessen, but never totally eradicate, the risk for TD may be suggested for tourists visiting high-risk areas. These include choosing foods and drinks in accordance with instructions, using preventive antibiotics instead of antimicrobial medications, and washing your hands carefully with soap when available. When handwashing is not an option, carrying tiny bottles of alcohol-based hand sanitizers (with 60 % alcohol) may make it simpler for travelers to wash their hands before dining. The majority of microorganisms that cause TD do not have vaccines; nevertheless, travelers should read up on the vaccines for cholera, hepatitis A, typhoid, and paratyphoid fever to avoid other food- or water-borne diseases to which they are vulnerable.

What Is the Treatment Given for Traveler's Diarrhea?

Replacement of lost fluids and electrolytes is crucial, particularly in young children and those with chronic medical conditions. Severe dehydration caused by TD in otherwise healthy adult travelers is uncommon unless vomiting lasts long. Replacement of fluid losses nonetheless continues to be an adjuvant to other forms of therapy and aids in the traveler's quicker recovery. Use only beverages that are sealed, chlorine-treated, boiled, or otherwise known to be purified; travelers should keep this in mind.

Oral rehydration solution (ORS), made from packaged oral rehydration salts, such as those offered by the World Health Organization, is the best replacement for severe fluid loss. In most underdeveloped nations, ORS is freely accessible at shops and pharmacies. Add one packet to the specified amount of boiled or treated water to make ORS, typically 1 liter. Due to their salinity, most ORS formulations may be quite unpleasant for travelers. Any palatable liquid, including sports drinks, can be used to maintain hydration in moderate cases. However, very sweet beverages like sodas might produce osmotic diarrhea if eaten in large quantities.

In cases where diarrhea is brought on by bacterial infections susceptible to the specific antibiotic prescription, antibiotics help cut the length of diarrhea by roughly a day. Antibiotics are sometimes used to treat TD. However, there are worries regarding adverse side effects. Travelers who take antibiotics risk picking up resistant microorganisms like ESBL-producing microorganisms, which could harm them (especially if they are immunosuppressed or women at risk for UTIs) and threaten the community.

Conclusion

Travelers and other people who eat or drink contaminated food or water might get traveler's diarrhea. It is a short but uncomfortable gastrointestinal infection frequently resulting in loose stools and abdominal cramping. Most of the time, bacteria are to blame. However, parasites or viruses can also be to blame. When visiting nations with less stringent sanitary regulations than their own, international travelers are most in danger.

Dr. Nagaraj
Dr. Nagaraj

Diabetology

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