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Measles Encephalitis - Causes, Symptoms, Diagnosis, and Treatment

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Measles encephalitis is an uncommon but severe consequence of the contagious viral measles. Read the below article.

Written by

Dr. Durga. A. V

Medically reviewed by

Dr. J. N. Naidu

Published At July 12, 2023
Reviewed AtNovember 1, 2023

Introduction

Measles encephalitis is a rare but possibly fatal consequence of the contagious viral measles. When the measles virus affects the brain, it causes swelling and inflammation, leading to convulsions, unconsciousness, and even death. Even though measles vaccination has considerably lowered the incidence of measles encephalitis, it remains a severe problem, especially in low-vaccination-rate populations. In this context, it is critical to comprehend the risk factors, clinical signs, diagnosis, and therapy of measles encephalitis and the preventative actions that may be implemented to lower the risk of infection and its sequelae. This article overviews measles encephalitis, focusing on clinical characteristics, etiology, and current therapy methods.

What Is Measles Encephalitis?

Measles encephalitis is an uncommon but severe consequence of the contagious viral measles. Measles encephalitis is caused by the measles virus infecting the brain and producing inflammation and swelling. This inflammation can harm brain cells, resulting in seizures, coma, and even death. Measles encephalitis is most common in children under five who have not been immunized against measles. Children with a weaker immune system, malnutrition, or vitamin A deficiency are more likely to develop measles encephalitis. Fever, headache, seizures, and changes in mental status, such as confusion or disorientation, can all be symptoms of measles encephalitis. A clinical examination, blood tests, and imaging procedures, such as magnetic resonance imaging (MRI) or computed tomography (CT), are commonly used to diagnose.

Clinical examination, blood tests, and imaging procedures, such as magnetic resonance imaging (MRI) or computed tomography (CT) scans, are commonly used to diagnose. Measles encephalitis treatment is primarily supportive and may include anticonvulsant drugs to manage seizures, corticosteroids to reduce inflammation, and intravenous fluids to keep patients hydrated. Some patients may require mechanical ventilators or other forms of care. Prevention is critical in the treatment of measles encephalitis. Measles vaccination is the most effective strategy to avoid infection and its consequences. Furthermore, good hygiene practices, such as hand washing and avoiding close contact with infected individuals, can help to prevent the spread of measles.

What Are the Causes of Measles Encephalitis?

  • The measles virus causes measles encephalitis, a highly contagious illness that spreads via the air when an infected person coughs or sneezes.

  • Contact with virus-infected things, such as toys or doorknobs, can also spread the virus.

  • The measles virus replicates in the respiratory tract first after entering the body, generating the usual measles symptoms of fever, cough, runny nose, and rash.

  • In some circumstances, however, the virus can enter the brain and cause inflammation and swelling, eventually leading to encephalitis.

  • Although anyone can get measles encephalitis, certain factors increase their chances.

  • These include being young, malnourished, lacking in vitamin A, and having a weakened immune system as a result of a disease.

  • It's important to emphasize that measles encephalitis is a rare complication of measles, and the vast majority of people who get measles do not acquire it.

  • However, due to the potential severity of the condition, measles vaccination is recommended for all eligible individuals.

What Are the Symptoms of Measles Encephalitis?

Measles encephalitis is a serious measles complication that can produce various symptoms affecting the brain and nervous system. Measles encephalitis symptoms typically appear a few days to a week after common measles symptoms such as fever, cough, runny nose, and rash.

Measles encephalitis symptoms may include:

  • Headache.

  • Fever.

  • Neck stiffness.

  • Light sensitivity.

  • Vision alterations.

  • Indecision or disorientation.

  • Restlessness or irritability.

  • Convulsions.

  • Paralysis or weakness on one side of the body.

  • Coma.

It's essential to note that the symptoms of measles encephalitis can vary greatly, and not everyone with this condition will have all of them. Furthermore, some of these symptoms can occur in other conditions.

How to Diagnose Measles Encephalitis?

A clinical examination, laboratory tests, and imaging studies are used to diagnose measles encephalitis.

  1. Clinical Examination: The doctor will first undertake a physical examination to assess the symptoms and check for signs of inflammation or edema in the brain. The doctor will also review the patient's medical history and enquire about any recent measles or other infectious illness exposure.

  2. Laboratory Tests: Blood tests can be used to detect antibodies to the measles virus or to detect the virus itself. A lumbar puncture (spinal tap) may also collect cerebrospinal fluid for study. The presence of the measles virus, as well as other signs of inflammation or infection, can be detected in cerebrospinal fluid.

  3. Imaging Studies: Magnetic resonance imaging (MRI) or computed tomography (CT) scan, for example, might be used to look for evidence of inflammation or swelling in the brain. These tests can also assist in ruling out other potential causes of symptoms, such as a brain tumor or stroke.

It is important to highlight that diagnosing measles encephalitis can be difficult because the symptoms are similar to those of other illnesses that affect the brain and nervous system. A medical expert must conduct a comprehensive examination to provide an accurate diagnosis. If one or someone you know has recently had measles and develops symptoms of encephalitis, seek medical assistance immediately. Early detection and treatment can help.

What Is the Treatment Plan For Measles Encephalitis?

Measles encephalitis is typically treated with supportive care and symptom management. Hospitalization may be required in extreme situations.

  1. Supportive Care: The purpose of supportive care is to keep important functions going and to avoid problems. This could include administering oxygen therapy, hydration, and nutrition via intravenous fluids. If the patient has seizures, anti-seizure medication may be administered.

  2. Antiviral Drugs: In some situations, antiviral drugs such as Ribavirin have been used to treat measles encephalitis. However, the effectiveness of these treatments is unknown, and they may only be beneficial in some patients.

  3. Corticosteroids: Such as Prednisone, can treat inflammation and edema in the brain. On the other hand, the use of corticosteroids for measles encephalitis is debatable because they may weaken the immune system and increase the risk of infection.

  4. Intravenous Immunoglobulin (IVIG): IVIG is a medicine that contains antibodies that can aid in the battle against the measles virus. Although the effectiveness of IVIG in treating measles encephalitis is unknown, it may be used in some cases.

It is essential to highlight that there is no specific treatment for measles encephalitis and that management is primarily supportive. The emphasis is on symptom management, preventing complications, and giving the best possible care to the patient. Preventing measles encephalitis is critical. Measles vaccination is highly successful in preventing the disease.

Conclusion

Measles encephalitis is an uncommon but deadly consequence of the measles virus that causes inflammation and swelling in the brain. While most people who get measles recover completely without complications, measles encephalitis can cause long-term neurological damage or even death. Early identification and treatment are critical for improving results and lowering the risk of complications. Treatment for measles encephalitis is primarily supportive, concentrating on symptom management and preventing complications. Vaccination is the most effective strategy to avoid measles encephalitis and other measles virus problems. Measles encephalitis is a reminder of immunization's significance against avoidable infections and the potentially devastating implications of not being immunized.

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Dr. J. N. Naidu
Dr. J. N. Naidu

General Practitioner

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