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Female Genitourinary Infections - Causes, Symptoms, Diagnosis, and Treatment

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Genitourinary infections are infections like urinary tract infections, vaginitis, and endometritis, that occur in the genital and urinary tract.

Published At February 21, 2023
Reviewed AtMay 9, 2024

Introduction:

Genitourinary infections are divided into urinary tract infections and genital tract infections. Urinary tract infections include cystitis and pyelonephritis. Genital tract infections include vaginitis (inflammation of the vagina), urethritis (inflammation of the urethra), cervicitis (inflammation of the cervix), genital ulcerative diseases, endometritis (inflammation of the lining of the uterus), and pelvic inflammatory disease. This article describes three common genitourinary infections, mainly urinary tract infections, vaginitis, and endometritis.

What Is a Urinary Tract Infection (UTI)?

Urinary tract infections occur in any part of the urinary system (bladder, urethra, and ureter). However, most infections occur in the urethra and bladder.

What Causes Urinary Tract Infection?

UTIs are most commonly seen in women. They occur through microorganisms like bacteria, fungi, and protozoa. The organism enters the urinary tract via the urethra and spreads to the bladder, causing infection and inflammation. Some other risk factors for UTIs include:

  • Inadequate water intake.

  • Not keeping the genital area clean or dry.

  • Sexual activity.

  • Kidney stones.

  • Certain types of birth control.

  • Menopause (period of the end of menstrual cycles).

  • A suppressed immune system(due to diabetes or other conditions).

What Are the Symptoms Seen in a Urinary Tract Infection?

Some symptoms of urinary tract infections include

  • A strong urge to urinate that does not go away.

  • Frequent urination but with small amounts of urine every time.

  • Pain or burning sensation while urinating.

  • Urine is bright pink or red and has a strong odor and cloudy appearance.

  • Blood in the urine.

  • Pain in the flank, center of the pelvis, and pubic bone of women.

  • Pain during sexual activity.

  • Fever with chills.

  • Tiredness.

  • Vomiting and nausea.

How Is Urinary Tract Infection Diagnosed?

Some of the tests done to diagnose urinary tract infections include:

  • Urine Analysis - The urine will be examined for bacteria and pus cells in urine analysis. The bacteria and pus cells found in the urine determine the presence of an infection.

  • Urine Culture - A urine culture determines the type of bacteria present in the urine and its sensitivity and resistance to certain antibiotics.

In the event of infection not responding to the treatment or is recurrent, the doctor might suggest further tests such as:

  • Ultrasound - Ultrasound imaging creates a detailed image of the internal organs.

  • Cystoscopy - A cystoscope (instrument with a lens and light source) is used to see the inside of the bladder from the urethral region.

  • Computed Tomography (CT) Scans - CT scans are done to obtain additional detailed images of the urinary tract regions.

How Is Urinary Tract Infection Managed?

  • Antibiotics are the first treatment choice for urinary tract infections. The overall health of the patient and the type of bacteria found in the urine is the deciding factor for medication.

  • Medicines for simple urinary infections include Cephalexin, Ceftriaxone, and Nitrofurantoin.

  • In case of a complicated UTI, the medicine of choice is Fluoroquinolone.

  • The UTI infections usually resolve within a few days after starting the medications.

  • The individuals are also advised to drink copious amounts of water.

What Is Vaginitis?

Vaginitis refers to vaginal infection or inflammation. Vaginitis mainly occurs during the reproductive years (late teens to early 40s).

What Are the Symptoms Seen in Vaginitis?

Some of the common symptoms seen are:

  • Itching and burning sensation in the vagina.

  • Vaginal discomfort and soreness.

  • Vaginal bleeding and blood spots.

  • Swollen, flushed, and inflamed skin around the vulva and vagina.

  • Color change and change in the amount of vaginal discharge.

  • Burning sensation and pain during urination.

  • Pain during sexual intercourse.

What Are the Types of Vaginal Infections?

Vaginal infections are distinguished from each other by their unique symptoms. The different types of vaginal infections include:

  1. Bacterial Vaginosis (BV) - Bacterial vaginosis is caused when the bacteria naturally found in the vagina overgrow. It does not cause much itching but has a thin greenish, grayish-white, or yellowish-colored discharge. This discharge usually has a fish-like odor which gets stronger after penetrative sex. BV is not a sexually transmitted infection, but sexual contact increases the chances of bacterial overgrowth.

  2. Atrophic Vaginitis - This condition develops after menopause or when estrogen levels drop. Atrophic vaginitis is not an infection but increases the chances of developing UTIs and vaginal infections. Symptoms are burning, vaginal itching, changes in discharge, and dryness.

  3. Yeast Infections - Yeast infections are caused by a fungus called Candida albicans. Factors like hormonal changes, stress, and antibiotics lead to the overgrowth of yeast, causing the infection. Here, swelling occurs in the labia or the skin folds outside the vagina. Symptoms like soreness, burning, and vaginal and vulval itching are also seen in vaginal infections. Vaginal discharges are lumpy and white with a texture resembling cottage cheese.

  4. Trichomoniasis - The parasite Trichomonas vaginalis causes this infection. It is contracted through oral, anal, or vaginal sex without protection. It causes both fish-like odor and vaginal itching. Swelling, inflammation, and irritation occur in the vulva and vagina. Vaginal discharges are frothy and greenish-yellow in color. Other symptoms include lower abdomen pain and pain during sex and urination.

How Are Vaginal Infections Diagnosed?

  • The healthcare provider will take a detailed history of vaginal infections, sexual history, and other health conditions.

  • A pelvic examination to check for inflammation or irritation, depending on the symptoms.

  • A sample of vaginal discharge for analysis is collected.

  • A swab test will be performed in the cervix to test for (sexually transmitted infections) like chlamydia or gonorrhea.

  • Urine samples will also be collected to test for other STIs.

How Are Vaginal Infections Treated?

  • Bacterial infections are treated with Metronidazole (in a cream, gel, or tablet form) or Clindamycin.

  • Yeast infections are treated with antifungal suppositories or creams.

  • Trichomoniasis is treated with Tinidazole or Metronidazole tablets.

  • Atrophic vaginitis is treated with Estrogen tablets or creams to reduce vaginal irritation and dryness.

What Is Endometritis?

Endometritis is an inflammation in the uterine lining affecting all layers of the uterus. Endometritis is the most commonly occurring infection in the postpartum period.

How Is Endometritis Caused?

Most cases of endometritis involve aerobic and anaerobic bacteria. These microbes travel from the vagina into the cervix, leading to inflammation and infection in the uterine lining. This condition is a result of the rupture of membranes during childbirth. The bacteria colonize these damaged, bleeding, or devitalized uterine tissue causing the infection.

What Are the Symptoms of Endometritis?

The first sign of infection is fever associated with abdominal pain and purulent and foul-smelling lochia (normal discharge from the uterus after childbirth). Abnormal vaginal bleeding and discharge are also noted.

How Is Endometritis Diagnosed?

  • Physical examination, like pelvic and abdominal examination, is done, and tenderness will be noted in the suprapubic and uterine region.

  • Abnormalities in vital signs like fever, hypertension, and tachycardia are present.

  • Samples will be collected from the cervix to test for the presence of bacteria that caused the infection.

  • A complete blood test and erythrocyte sedimentation rate (ESR) are done to know elevated levels of the total count or other parameters.

What Are the Treatment Options for Endometritis?

  • In the case of mild disease, oral antibiotics are given. Some of the antibiotics given include Doxycycline, Amoxicillin-Clavulanate, and Levofloxacin.

  • Intravenous antibiotics and hospital admission are usually recommended for patients with severe- to-moderate endometritis.

  • Significant improvement will be noted in the condition within 48 to 72 hours of medicines.

Conclusion:

Female genitourinary infections include urinary tract infections, vaginitis, endometritis, urethritis, cervicitis, and genital ulcerative diseases. Some conditions are sexually transmitted, while others are not. Most infections can be prevented and cured by maintaining personal hygiene and taking appropriate preventive measures and treatment at the right time.

Frequently Asked Questions

1.

What Are the Common Infections of the Genitourinary System?

The most common genitourinary infections are sexually transmitted infections, infections due to common pathogens including parasites such as Trichomonas vaginalis, bacterial infections such as Treponema pallidum, Neisseria gonorrhoeae, Haemophilus ducreyi, Chlamydia trachomatis, and viral infections such as herpes simplex virus, human immunodeficiency virus, human papillomavirus.

2.

What Causes Genitourinary Infections?

The most common causes of genitourinary infections are as follows:
- Parasitic infections such as Trichomonas vaginalis.
- Bacterial infections include Neisseria gonorrhoeae, Haemophilus ducreyi, Chlamydia trachomatis, and Treponema pallidum.
- Viral infections include human immunodeficiency virus, human papillomavirus, and herpes simplex virus.

3.

What Are the Various Types of Female Bladder Infections?

- Uncomplicated Bladder Infections: These are common infections caused by bacteria entering the urethra and affecting the bladder. 
- Recurrent Bladder Infections: It is the recurrence of bladder infection episodes.
- Complicated Bladder Infections: Underlying health conditions, including diabetes, kidney stones, pregnancy, or a compromised immune system, contribute to the increased susceptibility to infections of this nature.

4.

What Is the Female Genitourinary Tract?

The female genitourinary tract involves the urinary and reproductive systems in women. It includes organs such as the kidneys, ureters, urethra, bladder, vagina, cervix, uterus, and ovaries. The genitourinary tract is responsible for urine formation, storage, and excretion. It also affects reproductive processes such as menstruation, sexual intercourse, and childbirth.

5.

What Is the Most Serious UTI?

The most severe type of UTI (urinary tract infection) is pyelonephritis. It is an infection involving the kidneys. It usually occurs when bacteria from a lower UTI ascend to the kidneys, which can lead to severe complications if left untreated. The symptoms of pyelonephritis include high fever, chills, lower back pain, nausea, vomiting, and frequent urination.

6.

What Is the Best Management for a Bladder Infection?

The best treatment for a bladder infection is usually a course of antibiotics, as the most common cause of bladder infection is bacteria. The doctor will prescribe specific antibiotics. The duration of the treatment will depend on the type of bacteria and the severity of the infection. In addition to antibiotics, the doctors suggest drinking plenty of water, frequently urinating, and avoiding irritants such as caffeine and alcohol to relieve symptoms and support recovery.

7.

What Antibiotic Is Used for UTI?

Most doctors recommend trimethoprim-sulfamethoxazole or fluoroquinolones because they eradicate aerobic gram-negative bacterial flora but have minimal effect on the fecal and vaginal anaerobic flora and provide the best long-term treatments for uncomplicated urinary tract infections. Ciprofloxacin and levofloxacin are the most commonly used fluoroquinolones to treat urinary tract infections. The doctor may also prescribe Nitrofurantoin or Fosfomycin tromethamine to treat uncomplicated urinary tract infections.

8.

How to Clean the Bladder Naturally?

Cleaning the bladder naturally involves good hygiene practices for good urinary health. Still, the main method to clean out the bladder involves staying hydrated by drinking plenty of water to flush out bacteria and toxins from the bladder and frequently urinating, as emptying the bladder regularly helps prevent bacteria buildup and reduces the risk of urinary tract infections.

9.

What Is the Fastest Antibiotic for Treating a UTI?

The choice and function of antibiotics depend on the causative bacteria; however, some antibiotics may provide quicker relief of symptoms, such as fluoroquinolones like Ciprofloxacin or levofloxacin, and are often considered faster-acting antibiotics. It is important to note that the effects of antibiotics can vary based on several factors, including the specific causative organisms, the severity of the infection, and the individual's response to the medication.

10.

What Is the Difference Between a Urine Infection and Cystitis?

Cystitis is the inflammation or infection involving only the bladder. Cystitis specifically targets the bladder as a distinct type of urinary tract infection. A urinary tract infection encompasses infections occurring in various parts of the urinary system, such as the bladder, ureters, urethra, and kidneys. Hence, a urine infection can also involve other parts of the urinary tract.

11.

Is Coconut Water Good for the Bladder?

There is no direct effect of coconut water specifically on the bladder. However, coconut water is a hydrating beverage that can help maintain fluid balance, and also it may have mild diuretic properties which promote increased urine production. Thus, by helping to stay well-hydrated and increasing urination, drinking coconut water can support overall urinary health by flushing out toxins and diluting bacteria in the bladder.

12.

Which Fruit Is Useful for Urine Infection?

Many experts recommend cranberries for urinary tract infections as they contain proanthocyanidins, which may prevent bacteria from attaching to the urinary tract wall and may lower the infection risk. In addition, drinking unsweetened cranberry juice may be beneficial in supporting urinary health by increasing hydration of the body and frequency of urination which helps flush out toxins and bacteria.

13.

How to Get Immediate Relief From a Uti?

It is important to receive medical treatment for a urinary tract infection (UTI). However, there are some measures affected individuals can take for immediate relief of symptoms:
- Drinking plenty of water help to flush out bacteria from the urinary tract.
- Applying a heating pad over the lower abdomen can help alleviate pain and discomfort.
- Painkillers like Ibuprofen or Acetaminophen can temporarily relieve pain and reduce fever associated with a UTI.

14.

How to Sleep With a UTI?

- To comfortably sleep with a urinary tract infection 
- Limit evening fluid intake to reduce nighttime urination.
- Use a heating pad for comfort
- Urinate before sleeping at night. 
- In addition, taking a painkiller to relieve pain can help with a good night's sleep.

15.

Which Sleeping Position Is Best for UTI?

No proven specific sleeping position can be best for a urinary tract infection. However, the affected individual can try positions that can provide comfort, such as sleeping on the side to alleviate pressure on the bladder. The affected person can also use supportive pillows between their legs to sleep comfortably.
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Dr. Samer Sameer Juma Ali Altawil
Dr. Samer Sameer Juma Ali Altawil

Urology

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