Q. Received class 1 and 2 allergy for a few foods in RAST. Can those foods cause anaphylaxis?

Hello,

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RAST (Radioallergosorbent test) is a highly accurate test. If the test is positive for a specific allergen, it shows that you are sensitized to that particular allergen. This means that you may mount an allergic response when you are exposed to that allergen. However, it does not mean that you will necessarily have an allergic reaction to that substance and, nor does it mean that any reactions will be severe.

If the test is negative, it means that one does not have the ability to mount an allergic reaction to that allergen and any symptoms one may be experiencing are probably not due to an allergic reaction to that substance. However, the results of the RAST need to be interpreted in conjunction with your clinical history. e.g the presence of an allergy to some or a few allergens which may possibly be present either in the environment or food does not necessarily mean that they are responsible for the symptoms because if they are not even present in the environment or food of an individual, then they are irrelevant.

In your case, an elimination diet has not helped thus proving the fact that RAST test results should be carefully interpreted along with clinical history and does not necessarily mean that you will necessarily have an allergic reaction to the substance that you tested.

Angioedema is frequently associated with urticaria. Pathogenesis is the same for both urticaria as well as angioedema. The presence of angioedema does not always mean that it is a part of anaphylaxis. Angioedema can be a part of anaphylaxis in those individuals who have a severe allergic reaction to an allergen with high levels of antibodies circulating in the blood.

Since you have only class 1 and 2 level antibodies, therefore, it is unlike that these antigens or allergens would cause anaphylaxis.

Same symptoms doesn’t mean you have the same problem. Consult a doctor now!

Dr. Sushil Kakkar

Experience: 21 + Yrs

Dermatology

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