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Q. Kindly suggest medicines to minimize the muscle and nerve tightening and any new effective medicine for ankylosing spondylitis.

Answered by
Dr. Anshul Varshney
and medically reviewed by iCliniq medical review team.
This is a premium question & answer published on Feb 17, 2015 and last reviewed on: Oct 09, 2018

Hello doctor,

  • Seven years ago, I was affected by ankylosing spondylitis (HLA-B27 positive) (RF negative).
  • And then after a year, I was affected by pulmonary tuberculosis (TB lungs).
  • Tuberculosis was controlled within months and I continued taking medication for ankylosing spondylitis.
  • And then for a few months I had used homeopathy and ayurvedic medicines. 
  • Now I am on SAAZ-DS and NSAIDs.
  • Bilateral SI (sacroiliac) joint spaces are reduced and restricted forward movement and other joint movements.
  • I am doing light exercise, but in pain. It is a bit difficult.
  • Last month, as usual back pain knocked on my right side lower back, but this time muscles got tightened and in the morning when I wake up, pain is so severe.
  • Pain is so severe that, even pain killer does not work.
  • After few days, the pain disappears and one of the nerve on the same right side back feels like tightened and I feel something like electric shocks.
  • Even during sleep, when I wake up there is too much pain.
  • I get stuck in one position, but after standing and walking, the pain disappears gradually.
  • Again after few days, it reduces gradually but not completely.
  • I am now 28 years old and I weigh 66 Kg.
  • In the past few months my weight has increased about 6 Kg,

I am requesting you to kindly suggest medicines to minimize the muscle and nerve tightening and any new effective medicine for ankylosing spondylitis.

Dr. Anshul Varshney

Critical Care Physician Diabetology General Medicine Internal Medicine Medical Gastroenterology Nephrology Pulmonology (Asthma Doctors) Rheumatology


Welcome to

Following are the answers for your queries:

  • Get an  MRI LS spine done, to see for any disc prolapse as the pain you are describing along with tingling sensation is seen in disc prolapse only.
  • A combination of Pregabalin and Methylcobalamine will help you in neuropathy pain.
  • For ankylosing spondylitis, you can go for biological therapy drug like Rituximab.
  • Effective NSAID would be Etoricoxib. For severe pain you may take Tramadol.

Stay healthy.

Revert back with the reports to a rheumatologist online -->

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