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Is it advisable for B-ve girl to have a baby with O+ve boy?

This Premium Q&A, reviewed and published, features a real conversation between an iCliniq user and a physician.

Patient's Query

Hello doctor,

My girlfriend is B negative group and I am O positive group.

Is it advisable for us to get married or give birth?

Please help.

Thank you.

Hello,

Welcome to icliniq.com.

Yes, the blood group is not at all a barrier to your marriage. Your wife is Rh-negative, so she will be given anti-D immunoglobulin injection during pregnancy at the 28th and 34th week of gestation to prevent hemolytic disease of the newborn. So do not worry about that.

I will suggest one investigation before getting married, which is Hb electrophoresis by the HPLC (high-performance liquid chromatography) method, to rule out hemoglobinopathy, which should be done before marriage.

I hope this helps.

Thank you.

Medically reviewed byiCliniq medical review team

Published At June 30, 2018
Reviewed AtDecember 2, 2025

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