Q. If a person with chronic kidney disease receives Toradol 60 mg,can that lead to acute renal failure?

Hi,

Welcome to icliniq.com.

• Toradol contains Ketorolac. It is known to cause worsening of kidney functions.

• But usually what is seen is that, it is the administration for a longer duration which causes the increased probability of renal failure and not a single dose.

• A famous study reveals that ketorolac administered for 5 days or less did not increase the rate of renal failure.

• However, among patients who were treated with analgesics for more than 5 days, ketorolac may be associated with an elevated rate of acute renal failure.

• So, in my opinion, that person should drink plenty of water if otherwise not contraindicated, so as to keep the kidneys well hydrated.

• He/she should get a repeat evaluation of serum creatinine after 3 days of getting the injection (Toradol intramuscular injection).

• If the acute renal failure has to occur, it usually occurs in the first 3-5 days only.

For further queries, consult a nephrologist online --> https://www.icliniq.com/ask-a-doctor-online/nephrologist

Hi,

Welcome to icliniq.com.

• Yes, if we compare the tolerance of a young person's kidneys to a person of 65 years of age, the kidneys of the older would decompensate easily.

• However, as per my experience and the studies, the single dose would not affect much. 

• As discussed earlier, he/she should consume good quantity of water (if not contraindicated) and wait and watch.

• Get the serum creatinine evaluated after 3 days of exposure.

• A rise of ≥1.5 times baseline is considered as acute kidney injury.

• So, take the precautions as discussed. 

• As far as pain killers are concerned, if he/she requires them, then Tramadol is the best drug which is relatively very safe in kidney dysfunctions.

Take care.

For further queries, consult a nephrologist online --> https://www.icliniq.com/ask-a-doctor-online/nephrologist

Same symptoms doesn’t mean you have the same problem. Consult a doctor now!

Dr. Anshul Varshney

Experience: 14 + Yrs

Internal Medicine

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