Q. If a person with chronic kidney disease receives Toradol 60 mg,can that lead to acute renal failure?

Answered by
Dr. Anshul Varshney
and medically reviewed by iCliniq medical review team.
This is a premium question & answer published on Jun 27, 2015 and last reviewed on: Sep 20, 2019

Hello doctor,

If a person with chronic kidney disease with a creatinine of 1.9 and a GFR of 40 receives Toradol 60 mg IM as a single dose, can that lead to acute renal failure? How soon would failure occur after the administration of the medication?

#

Hi,

Welcome to icliniq.com.

  • Toradol contains Ketorolac. It is known to cause worsening of kidney functions.
  • But usually what is seen is that, it is the administration for a longer duration which causes the increased probability of renal failure and not a single dose.
  • A famous study reveals that ketorolac administered for 5 days or less did not increase the rate of renal failure.
  • However, among patients who were treated with analgesics for more than 5 days, ketorolac may be associated with an elevated rate of acute renal failure.
  • So, in my opinion, that person should drink plenty of water if otherwise not contraindicated, so as to keep the kidneys well hydrated.
  • He/she should get a repeat evaluation of serum creatinine after 3 days of getting the injection (Toradol intramuscular injection).
  • If the acute renal failure has to occur, it usually occurs in the first 3-5 days only.

For further queries, consult a nephrologist online --> https://www.icliniq.com/ask-a-doctor-online/nephrologist

Thank you doctor,

The person is 65 years old. Will the kidneys decompensate quicker?

#

Hi,

Welcome to icliniq.com.

  • Yes, if we compare the tolerance of a young person's kidneys to a person of 65 years of age, the kidneys of the older would decompensate easily.
  • However, as per my experience and the studies, the single dose would not affect much
  • As discussed earlier, he/she should consume good quantity of water (if not contraindicated) and wait and watch.
  • Get the serum creatinine evaluated after 3 days of exposure.
  • A rise of ≥1.5 times baseline is considered as acute kidney injury.
  • So, take the precautions as discussed. 
  • As far as pain killers are concerned, if he/she requires them, then Tramadol is the best drug which is relatively very safe in kidney dysfunctions.

Take care.

For further queries, consult a nephrologist online --> https://www.icliniq.com/ask-a-doctor-online/nephrologist


Was this answer helpful?

 | 


Related Questions:
I have excessive thirst and frequent urination. Are these due to my medications?

.. seen your detailed reports (attachment removed to protect patient identity). Lithium commonly causes two types of renal disease, namely nephrogenic diabetes insipidus and chronic tubulointerstitial nephritis. Diabetes insipidus i...   Read full

If a person with chronic kidney disease receives Toradol 60 mg,can that lead to acute renal failure?

.. Ketorolac. It is known to cause worsening of kidney functions. But usually what is seen is that, it is the administration for a longer duration which causes the increased probability of renal failure and not a single dose. A famous study reveals t...   Read full

My mother is suffering from chronic kidney disease. Can she avoid dialysis?

She has a history of diabetes for the past 25 years ... Even if your mother is not experiencing any of the above symptoms, depending on her history of chronic diabetes and levels of creatinine cl...   Read full

 

This is a sponsored Ad. icliniq or icliniq doctors do not endorse the content in the Ad.

Also Read Answers From:

ideaComprehensive Medical Second Opinion.Submit your Case

Also Read


Can viral fever lead to Parkinson's disease?
Hello doctor,I had a viral fever six years back. I had a very high temperature of 105, bad cough, also hallucinations. I...  Read more»
Parkinson's Disease: Historical Aspects and Current Treatment Approaches
This article discusses the historical aspects of Parkinsonism and, the evidence based approaches currently available for...  Read more»
Frequently Asked Questions About COVID-19 Vaccines
COVID-19 vaccines can be a real lifesaver. Read this to know the answers to the common questions and doubts on COVID-19 ...  Read more»

Ask your health query to a doctor online?

Ask a Nephrologist Now

* guaranteed answer within 4 hours.

Disclaimer: No content published on this website is intended to be a substitute for professional medical diagnosis, advice or treatment by a trained physician. Seek advice from your physician or other qualified healthcare providers with questions you may have regarding your symptoms and medical condition for a complete medical diagnosis. Do not delay or disregard seeking professional medical advice because of something you have read on this website.