Chronic Kidney Disease

Chronic kidney disease (CKD) is a long-lasting decline in kidneys' functioning, usually lasting longer than three months. CKD occurs in five stages, where mild damage is stage 1, and complete failure of kidney functions is seen in stage 5. CKD commonly occurs due to high blood pressure and sugar and can result in anemia, bone disease, and heart problems.

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My mother is having vesicoureteral reflux. Is it a life-threatening condition?

Query: Hello doctor, My mother has vesicoureteral reflux, which was diagnosed 20 years ago. At that time, her left kidney was functioning 27 % and her right kidney 72 %. She is getting tired and she is a heavy drinker and smoker. Should I be concerned for her? She does not want to see a doctor. Is her cond...  Read Full »

Dr. Rahul Suresh Kulkarni

Answer: Hi, Welcome to It is strongly advised that your mother gets a kidney function tests like serum creatinine, blood urea, and nitrogen. She should at least try to reduce her smoking and drinking, as it would further contribute to the worsening of the kidney function. If possible, she shoul...  Read Full »

What are the preventive measures to be taken to prevent blood clots during dialysis?

Query: Hi doctor, I am a retired person aged 69 years. I am a CKD patient on dialysis for the last three years. Recently, the fistula on my left hand has been blocked. Through venogram, it is seen that it could not work anymore. Due to the blood clots, the flow has been distributed; hence permacath was pl...  Read Full »

Dr. Parth R Goswami

Answer: Hi, Welcome to Following is my opinion for your asked question. Actually, during dialysis, it is common to form a blood clot, and the reason behind this is a disturbance of blood flow during dialysis. Therefore, Heparin or some other anticoagulant can be given before and during dialys...  Read Full »

Will fluctuations in GFR cause chronic kidney disease?

Query: Hi doctor, I am 53 years old with a weight of 80 kilograms and a height of five feet seven inches. I have been athletic most of the time. But still, I gained some weight over the past few years. In these few years, I have done some general tests. Initially, my GFR was 73 at the age of 45. At the ...  Read Full »

Dr. Nasir

Answer: Hi, Welcome to The presence of chronic kidney disease cannot be predicted only by the values of GFR (glomerular filtration rate). It also depends on the presence and absence of protein in the urine. It is good to do a urine routine and microscopy test to know whether there is a...  Read Full »

Did I develop kidney disease because of prolonged use of Pantoprazole?

Query: Hello doctor, I am a 35-year-old male. I am 70 inches tall and weigh around 195 pounds. I go to the gym and frequently exercise, mostly weightlifting. I take 5 g of creatine monohydrate daily. I also take 40 mg of Pantoprazole daily and 40 mg of Famotidine daily for acid reflux. I have been on this ...  Read Full »

Dr. Manzoor Ahmad Parry

Answer: Hello, Welcome to People who take creatine supplements are expected to have higher creatinine levels that do not necessarily mean low eGFR (estimated glomerular filtration rate). However, you have slightly hazy protein in urine examination. All other investigations look normal to me. ...  Read Full »

Kindly suggest the prognosis of CKD.

Query: Hi doctor, My girlfriend is 35 years old. She is obese, exercises regularly and tries to watch her diet. In spite of these, she is prediabetic. Her fasting blood glucose is typically around 105 mg/dL. Her A1C is normally in the range of 5.7% to 6%. She takes Metformin to manage the prediabetes. Her...  Read Full »

Dr. Anshul Varshney

Answer: Hi. Welcome to We are here to help you. Considering her prediabetes a cause of her proteinuria, yes, she would be categorized in stage 1 CKD (chronic kidney disease). However, that is very unlikely that such a prediabetes at this age is going to cause proteinuria. Yes, this is not...  Read Full »

Are raised kappa levels seen in multiple myeloma?

Query: Hi doctor, I have been diagnosed with CKD, and my GFR is 52. My recent blood test results show the following information. Kappa QNT free LT chains 41.60 mg/dL, lambda QNT free LT chains 0.96 mg/dL, KAP/LAM free LT chain ratio 43.33 and hemoglobin 15.8 g/dL. I was also detected with vitamin D deficie...  Read Full »

Dr. Anshul Varshney

Answer: Hi, Welcome to We are here to help you. A diagnosis of any disease is based on the symptoms and laboratory work. I need the following details to help you better. Why were these tests performed? Do you have bone pain or any night sweats or any weight loss? Please attach a scanned cop...  Read Full »

What causes swelling in one leg and foamy urine?

Query: Hi doctor, I had some pain in my flank for the past four months and so I consulted the doctor. I have taken some scans of my liver and kidney. But nothing was determined and so I was asked to do a kidney function test. I got a creatinine level of 4.2 mg/dL and urea of 60 mg/dl. Both of the values...  Read Full »

Dr. Penchala Prasad Kandikattu

Answer: Hi, Welcome to If you had renal failure, then you will have developed bilateral pedal edema. But unilateral pedal edema occurs due to gout or cellulitis or DVT (deep vein thrombosis). This condition needs proper examination. Please mention whether you had a creatinine level of 4.2 mg/...  Read Full »

Will intake of Lo Loestrin Fe cause problems in kidney functioning?

Query: Hi! I’m a 24 year old female who recently had a BMP drawn and my GFR is 81 creatinine 0.86. The only medication I take is Lo LoEstrin Fe OCP. The 12 hours before the lab test I had limited water intake and didn’t know if this would effect the results at all. I am stressing myself out kno...  Read Full »

Dr. Nasir

Answer: Hello the way in the creatinine clearance is calculated is by collecting 24 hour urine and then examining it for both proteins and creatinine. when 24 hour urine is collected it will give us a clear Idea as to what is happening in the body. measurements made from spot samples or not very accurate a...  Read Full »

Does my mother's CT scan show the cause of weakness?

Query: Hello doctor, My mother's present complaint is weakness. She is also suffering from diabetes, blood pressure, CKD and heart problem. We have done the CT scan. The CT scan shows shortness of breath in the lung. I am sending the report of a CT scan and other prescriptions. Please advise.  Read Full »

Dr. Amolkumar W Diwan

Answer: Hi, Welcome to I have read all the reports attached here (attachment removed to protect patient identity). Your mother is a known case of diabetes mellitus, chronic kidney disease and blood pressure. Her CT chest is suggestive of left upper lobe density. Here the question is whether it ...  Read Full »

What are the treatment options for the patient with high creatinine and GFR values?

Query: Hi doctor, I want to consult a nephrologist for my 54-year-old mother. She has high creatinine at 164 and eGFR at 31. She also has high blood pressure for the past 15 years, for which she takes Amlodipine 5 mg once a day. No other medicines and she does not have diabetes. We got her blood tests don...  Read Full »

Dr. Manzoor Ahmad Parry

Answer: Hello, Welcome to I checked the reports of your mother (attachment removed to protect patient identity). It shows features of CKD (chronic kidney disease) with the possibility of renovascular disease. CT (computed tomography) angiography will be a good choice to rule out any ren...  Read Full »

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