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Pupil Dilation - Causes, Symptoms, Diagnosis, and Treatment

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Pupil dilation refers to the expansion of the pupil that is usually in response to light variations in the environment. Read more about the topic in detail.

Medically reviewed by

Dr. Shikha Gupta

Published At March 21, 2023
Reviewed AtJune 23, 2023

Introduction:

The pupil is a dark adjustable circular opening in the center of the eye that enlarges or contracts to let light enter. The average pupil size ranges between 2.5 to 4.0 millimeters. However, it can approach a maximum size of three to eight millimeters. The pupil plays an essential role in our vision, similar to the camera's aperture allowing images to be seen and captured. The iris is a flat ring-shaped membrane located behind the cornea. It is made up of muscle fibers and connective tissues providing the ability to control the amount of light that enters the pupil by using particular muscles. The muscular iris moves to shrink the pupil. In daylight, the pupils become smaller, and wider at night, making them grow larger. It is an involuntary function controlled by the brain.

What Is Mydriasis?

Sometimes the pupils can dilate unusually without any change in the light; this medical condition is known as mydriasis. It is also termed as fixed pupils. Pupils are dilated when the black center of the eye is more significant than usual. The majority of the time, dilated pupils will naturally return to their usual size. Usually, the size of the pupils in each eye is the same. Anisocoria is the medical term for mydriasis that only affects one eye.

What Are the Common Causes of Dilated Pupils?

The most common causes of dilated pupils are -

1. Eye Examinations - During eye exams, eye professionals may apply special eye drops called mydriatics to dilate the pupils. After this procedure, the pupils will dilate for 15 to 30 minutes, enabling the specialist to obtain a clear view of both the retina and the optic nerve. Observing these parts of the eye can offer important clues about eye health and warning signs of significant issues.

2. Medications - Few medications can affect the muscles that control pupils and result in pupil dilations, such as:

  • Anti-seizure medications.

  • Antihistamines.

  • Medications for Parkinson's disease.

  • Antidepressant medications.

  • Antinausea medications.

3. Eye Injuries (Trauma) - Some eye injuries, such as eyeball fractures or orbital fractures, can disrupt the nerves or iris muscles that control pupil size. Pupil dilation may also occur following eye surgery, such as cataract removal or corneal transplant.

4. Sexual Stimulations - Increasing oxytocin levels generally induces the pupils to dilate. Oxytocin is a hormone and neurotransmitter that acts as a chemical messenger during sexual arousals and also helps women through labor, encourages parent-child interaction, and influences testosterone levels.

5. Head Injury - After a brain tumor, stroke, or head accident, the pressure that builds up inside the brain may damage the iris muscles that control the pupil’s natural opening and closing.

6. Illicit Drugs Usage - Pupil dilations are the primary key indicators for someone who has used illegal drugs such as Cocaine, amphetamines, ecstasy, etc. The pupil dilations are controlled by two muscles, muscles of the iris and the sphincter muscle. Depending on the drugs being taken, the neurotransmitters in the brain that helps to control pupil dilation are affected, causing the pupils to dilate. In addition, the sympathetic and parasympathetic nervous systems are affected by drugs, which causes pupil dilation. The parasympathetic nervous system regulates an individual's autonomic physiological functions while resting and causes the sphincter reaction. The sympathetic nervous system regulates the body's fight-or-flight reaction and activates the dilator in the eye.

7. Anxiety - Sometimes, anxiety may also lead to pupil dilations due to the release of adrenaline. Adrenal glands release chemicals and hormones that cause the body to go into fight or flight mode by sending nerve impulses to organs. An increase in heart rate, blood pressure, dilated pupils, and profuse sweating can all be signs of stress-induced adrenaline hormone reactions.

What Are the Signs and Symptoms of Pupil Dilation?

The signs and symptoms of pupil dilation depends on how the light enters the eye. The symptoms include:

  • Distorted vision.

  • Vey sensitivity to light.

  • Headache.

  • Dizziness.

  • Eye irritation.

  • Sleep Disturbance.

How Can Pupil Dilation Be Treated?

The treatment for pupil dilation is carried out by initially assessing the cause and following the required medical interventions. The full functionality of the eyes can be protected using various treatment modalities. Dilated pupils usually resolve independently without treatment, especially if eye drops cause them. Therefore, many medical professionals would only advise patients to wait for the drug's effects to subside and avoid it. Additional treatment is required for more severe cases of mydriasis includes:

1. Wear Sunglasses

For the majority of patients, light sensitivity is their main issue. They may feel uncomfortable, especially on a sunny day, because their pupils cannot close to block out excess light.

Dilated pupils are more sensitive to sunlight than usual. Avoid such situations and wear sunglasses while going outside, even indoors, until the medication's effects wear off. Having someone pick up from an appointment is preferable because driving is dangerous due to blurred vision and light sensitivity.

2. Surgery

In severe cases, surgery may be necessary for the brain and eye injuries to reconstruct the nerves or eye structures.

3. Artificial Contact Lenses

Artificial contact or prosthetic soft lenses can help mydriasis patients by effectively blocking the light and removing uncomfortable visual disturbances. Iris occlusion prosthetic contact lenses are advisable for patients with dilated pupils, glare, and photophobia (discomfort for sources of bright light) complaints.

4. Rehabilitation for Drug Abuse

If anyone suspects drug abuse from family or friends, there are multiple ways to help the situation. It may be helpful to know which drugs produce dilated pupils, but it is also critical to learn more about their unique problems to help them find the best course of treatment.

Speak up and express concern to them. Instead of making accusations or passing judgment, share the observations and support with them. It is essential to assist them and motivate them to visit a drug recovery center for assistance. Let them take responsibility for their actions, which is a crucial step on their journey to recovery.

Conclusion:

Pupil dilation usually occurs based on the variations of light. Mydriasis may develop from various causes, such as minor side effects from medications, eye and brain injuries, anxiety, and illicit drugs. If someone experiences the same signs and symptoms, advice to contact any eye care professionals as early as possible.

Frequently Asked Questions

1.

What Does a Dilated Pupil Mean?

In healthy individuals, pupils dilate under low light. Sometimes, few medicines, injuries, or eye diseases can cause dilation of pupils. Some of the medicines that cause pupil dilation are Atropine (reduces body secretions during surgery), Antihistamines (anti-allergic medicine), Decongestants (relieves nose block), and Tricyclic antidepressants (medicine to treat depression). Injury to the brain or eye and eye surgery can also cause pupil dilation. Specific conditions like benign episodic unilateral mydriasis cause dilatation of the pupil in one eye.

2.

What Is Considered Normal Size for Pupils?

The normal pupil size for adults is considered to be between 2 to 4 millimeters in bright light and 4 to 8 millimeters in the dark. Both pupils are normally of equal size. However, pupil size tends to reduce with age.

3.

How Much Pupil Dilation Occurs When Attracted to Others?

When attracted to others, pupils dilated as much as 45 percent. This is caused due to the influence of love hormones oxytocin and dopamine on pupil size. When attracted to someone, these hormones surge in the brain, increasing pupil dilation.

4.

What Emotions Do Small Pupils Reveal?

Small pupils produce an empathic socioemotional response that can be compared with emotional tears. In anger or negative emotions, pupils tend to reduce in size. Individuals who are sad or interested in their pupils tend to elicit a feeling of withdrawal.

5.

Can a Phone Be Used After Pupil Dilation?

Talking on the phone is not a problem. But staring at a phone screen when pupils are dilated can cause discomfort. Since phone or computer screens emit blue light, it can strain the eye. One must wait until the pupil returns to normal size. 

6.

Can Dilated Pupils Indicate Stress?

Recent studies have revealed that pupil dilation can reveal the amount of mental stress during multitasking. When the body undergoes stress, it triggers the autonomic nervous system's sympathetic branch, known for inducing flight or fight response. This mechanism could produce pupil dilation.

7.

How Long Can Pupils Remain Dilated?

It normally takes 4 to 24 hours for the pupil dilation to become normal. Children's pupils may remain dilated for 24 hours or longer. Individuals with lighter eye colors can also have dilated pupils for about 24 hours.

8.

Can Anxiety Induce Pupil Dilation?

During anxiety, the body is flushed with adrenaline hormones. This hormone prepares the body for a flight or fight response. One of its mechanisms includes pupil dilation. The dilated pupils allow more light within the eyes, enabling them to see dangerous things quickly.

9.

Can Being Sad Cause Pupil Dilation?

Sadness is a negative emotion depicting emotional pain, loss, grief, or despair. Severe sadness may also result in depression. Pupil size is an indicator of sadness. However, pupil size tends to decrease to express sadness more intensely.

10.

Can Pupils Dilate When Angry?

During anger, the person's emotion activates a sympathetic branch of the autonomic nervous system. This, in turn, stimulates flight or fight response. The emotion of aggression and raised adrenaline levels will result in pupil dilatation. This feature will add to the frightening appearance of the aroused individual.

11.

What Are the Steps to Return the Pupil to Normal Size?

In healthy patients, pupil dilation due to natural triggers or eye drops returns to normal without treatment needs. However, in severe cases, it protects the eyes from sunlight sensitivity. Prosthetic eye lenses may be worn to improve the pupils' appearance damaged by trauma. Injured eye tissue may need surgery.

12.

Can Lack of Sleep Cause Pupil Dilation?

When there is a lack of sleep, pupil size tends to be less stable. Sometimes, it can dilate to an extent or construct rather than maintain its size. In most individuals, pupil size tends to decrease due to fatigue in maintaining dilated pupils. The muscle that supports the pupil may experience fatigue and reduce pupil size.

13.

Does Eye Dilation Harm Vision?

A few hours following the eye exam, there may be blurriness and sensitivity to sunlight. These are caused by pupil dilation. Therefore, activities like driving soon after an eye exam must be avoided. The symptoms tend to improve four to six hours after the eye exam.

14.

Can Eye Dilation Become Permanent?

In individuals with brain injuries caused by head trauma, tumor, or stroke, the muscles in the iris get damaged. These muscles are responsible for the adjustment of pupil size. The injury caused one or both pupils to become dilated and unresponsive to light.

15.

Which Nerve Supplies the Pupil?

The optic nerve induces an autonomic response of the eye by causing changes in pupil size. The oculomotor nerve innervates pupillary muscles and causes constriction of pupils. The facial nerve can induce pupil dilation of the sympathetic nervous system and constriction through the parasympathetic nervous system.
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Dr. Shikha Gupta
Dr. Shikha Gupta

Ophthalmology (Eye Care)

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