How can high ALT be managed?

Hello,

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Well there is obvious surge in liver enzymes than previous year, but thankfully they are just at the upper limit of the normal. This minor elevation of ALT (alanine transaminase) and AST (aspartate aminotransferase) but seemingly within normal limits is not an alarming sign. Therefore, I want to assure you not to worry. But we just need to monitor it for a while to make sure it is not inclining in coming few months.

It seems it is your weight with accompanying some fatty deposition within the liver, which has been causing this distrubance of LFTs (liver function test). The condition is called fatty liver disease. The one reason is weight and the other reason is alcohol intake. I want to know if you have any history of taking alcohol? If you do not use alcohol then it is highly possible that your weight is causing all this. Your Body mass index (BMI) is 27.5 which is just an 2.5 higher than expected i.e. 55.11 lbs /m2.

For now I suggest you to try to lose some weight. like 10% of your current body weight i.e., target of 149.9 lbs. If not possible then at least try to reach 154 lbs in coming 3 months. I see this is decent goal. Just repeat a complete LFTs in 4 weeks time and let me know. If you have been using some herbal medicine, or any allopathic medications or any new treatment for any reason kindly let me know. I have seen your reports (attachment removed to protect patient identity) and they all are normal , but want to know whether you have any diabetes or cholesterol issues. Kindly upload those tests as well if you have.

Hello,

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The raised GGT again signifies that it is related to fat deposition within the liver. You did not mention about the pain in your previous thread so I did not correlate your upper limit of normal values of ALT, AST, and GGT with this pain. Because fatty liver disease tend to cause painless, completely asymptomatic elevation of the liver enzymes. Given pain, the scnerio can change however, and therefore I would need following information before establishing something conclusive out of it.

Do you take alcohol? Any herbal medicines? Or any OTC (over the counter) or prescription medicine in regular use? Did you have any of your ultrasound abdomen? The pain ever occurred before? Similar pain in past I mean? Any weight loss? Let me know the answers, I would be in better position to tell what you should do now. The possibilities are still on top fatty liver disease, alcohol related liver disease, gall bladder stones or gall bladder functional pain.

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Hi,

Welcome back to icliniq.com.

So as far as I understand the pain is mild, more of a dull ache like and does bother your sleep. This means pain is not as predominant feature of your overall scenario. Given no alcohol intake, no recent medicine, and recent gain in weight, the high possibility is fatty liver disease unless excluded otherwise. Since you have liver enzymes just at upper limit of the normal, I suggest you to simply reduce weight for now and just monitor the liver function tests every monthly.

A 7 to 10 % weight reduction of your current body weight would make these liver function tests improved. If you have difficulty with that at least control weight as it should not go above current value. Your current Body mass index BMI is 27.5. Less than 25 is normal. And that is what your target is. If your liver function test would not improve in one month time, would definitely suggest you some more blood work.