What can be the reason for sudden uneasiness and weakness?

Hello,

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Well, a single episode with the symptoms of uneasiness and weakness is most of the times nonspecific or due to a mild anxiety attack. If such is the case you should not be worried about it. But, if such episodes are frequent and come repeatedly, then definitely it should be thoroughly investigated. Though her BP (blood pressure) is slightly on the higher side, it is not as high as to cause sudden onset and prolonged uneasiness. To be on the safer side, I would like to suggest very mild antihypertensive and anxiolytic for a short duration. But before that, I would like you to get few investigations done on empty stomach and let me know the reports.

1. Complete hemogram.
2. T3, T4 and TSH (thyroid stimulating hormone).
3. ECG (electrocardiogram).

Another important factor to consider for her is that it may also be related to menopause, which can lead to hormonal disturbances, anxiety, uneasiness, hot flushes, mood disturbances and intolerance to mild/moderate heat and cold. So, kindly let me know about any recent changes in her menstrual cycles so that I can evaluate that aspect too.