Can high IgE cause persistent itching despite medicine?

Question

Hello doctor,

For two months, I have been itching in different parts of my body. But, I had the medicines from two weeks back only. My lab test results under serology include an IgE at 527.62 kU/L. I have been on these medicines for two weeks, Animus-L one in the night and Softin one in the morning. The medicines got over the day before yesterday. But, the itching persists in different parts of the body, from the head to the legs.

Please advise.

Thank you.

Answer 1

Hello,

Welcome to icliniq.com.

You seem to have severely elevated IgE levels, which are pointing towards atopy or an allergy. There must have been some offending agents that caused this reaction. We must find out what has caused the allergy in you. This can be achieved by comprehensive allergy profile testing or by skin prick testing. I strongly suspect some food allergens.

Before that, we need to control your allergy medically and also have a thorough history of the problem. I would suggest you take the Montair-Fx tablet (Montelukast and Fexofenadine) once in the morning with Lorfast (Loratadine) 10 mg tablet once at night. This, along with Dermocal Plus lotion applied on the areas of itching or rashes. Wait for two days before changing the medicines or adding a steroid to the same. Consult your specialist doctor, discuss with him or her, and take the medicines with their consent.

Please provide more details about your problem. If you can, please attach pictures of the rashes. Do share with us your previous medical records to help us understand the condition better. Please tell us more to find out the cause of the allergy. Kindly tell us when and how the problem started, how long you have been suffering, whether there is any relief or any aggravation with those medicines, whether you have any seasonal relationship to this problem, and whether you have a running nose, sneezing, nose blockage, or postnasal drip, headache, facial pressure, or reduced sense of smell, etc.

ImmunoCAP (capture) testing, which is a comprehensive blood allergy profile, is a blood test that tests for food and aeroallergy in you.

A skin prick test does the same but uses multiple small pricks on your forearm to find out an allergy sensitivity. Though many prefer a blood test, the skin prick test is regarded as the gold standard for testing specific allergies. Once we find out the offending agent, we can help you avoid the particular agent in your life and lead an allergy-free life.

I hope this helps.

Please revert so I can assist you further.

Thank you.