What causes high lymphocyte count?

Question

Hello doctor,

According to my CBC report, I am just above the normal lymphocyte count.

Does this range come under lymphocytosis?

Also, I have read that AIDS could be one of the causes of lymphocytosis. But I am confused because I thought AIDS destroys lymphocytes, which causes lymphocytopenia.

Please help me with my doubt.

Thank you.

Answer 1

Hello,

Welcome to icliniq.com.

I read your query, and I can understand your concern.

HIV (human immunodeficiency virus) infection reduces the lymphocyte count. However, HIV cannot be diagnosed by a CBC (complete blood count) test. CMIA (chemiluminescent magnetic microparticle immunoassay) tests or ELISA (enzyme-linked immunoassay) tests should be done to exclude the possibility of HIV infection.

HIV testing should be done if any unprotected sex or blood transfusion history is present. In your CBC report, a high lymphocyte count might be due to viral infection. I would suggest repeating your CBC test after a few days. And if you have any clinical complaints, kindly mention them.

I hope this solved your doubt.

Let me know if I can assist you further in solving your queries.

Thank you.

Answer 2

Hello,

Welcome back to icliniq.com.

I can understand your concern.

My opinion regarding your questions is that lymphocytosis is not a diagnostic test for HIV infection. In HIV-infected patients, lymphocytopenia is usually seen during the late stages of the syndrome, but it is not a diagnostic test for HIV infection.

Your attached report (attachment removed to protect the patient's identity) is HIV negative. You have investigated the combo test, which detects both antigens and antibodies. So even after nine years, it can still rule out HIV infection. You need not worry about HIV now if there is no further exposure.

I hope I have answered your question.

Let me know if I can assist you further.