How does Primolut-N help in treating PCOD symptoms?

Hello,

Welcome back to icliniq.com.

I understand your concern.

Let me give you a few facts on PCOD. PCOD (polycystic ovarian syndrome) is a congenital condition; I mean, it is genetically programmed, and you get it from your parents. When you suddenly put on weight, this cholesterol is converted into estrogen hormone (if I may simulate, have not you seen obese men developing breast and in young obese girls, who develop periods at a younger age they all have high levels of estrogen hormone or female hormone). In your body too when fat, which is a store for tomorrow, is more than normal, this is converted to the hormone which tips the balance between FSH (from the brain) and the ovarian hormone.

FSH (follicle-stimulating hormone), as the name suggests, stimulates the follicle from the ovary, but once the follicle is big enough to ovulate, the FSH is suppressed by the same estrogen hormone from the ovary (negative feedback). But when the same estrogen hormone is coming from fat, the brain is confused, and follicle growth stops early at a smaller follicle size (as the same estrogen level is sensed by the brain) and will not rupture; next scan, you will see all these follicles as PCOD. This is usually associated with obesity, irregular cycles, no periods for a few months, and later heavy periods with clots and fleshy masses spotting on and off, Thyroid abnormality, and prolactin problem indirectly. You develop that extra pad of fat around the mid-segment of the body, especially the waist, thighs, and breasts, with no fat beyond the elbow and knees. Excessive body hair growth, hair fall, a dark shade over the lower half of the face, acne, oily face skin, black skin over the back of the neck, inner thighs, and under the surface of the breast. May have a family history of diabetes, especially father or his family. This will not allow ovulation to occur at a time and so you cannot get pregnant till treated. It also increases your chances of early pregnancy abortions. But this has a solution.

Your weight has to be,

Weight in kilograms (kgs)= Height (in centimeters) - 100.

Your expected weight is 52-57 kgs.

Once you reduce weight to the normal range, you will not need any medicine to get periods.

To reduce weight, I suggest,

• No fasting, junk food, fast foods, red meat, and reduced snacks between meals.
• Have low calories food, high proteins.
• Regular exercise (especially for the waist and hip area), aerobics, yoga, brisk walking( swing your hands well), and trying to reduce two to four kgs per month. Do not hurry on weight reduction, as it will be difficult to maintain.
• As soon as you reduce at least five kgs, you will see changes.
• Even if you are in the normal weight range, try this schedule. It will help.

Myo-Inositol, chromium, and N-Acetyl cysteine are supposed to improve ovulation, but nothing is going to work unless you reduce weight. Instead, you can have Metformin one gram at bedtime, and it will reduce your insulin resistance and also help you in reducing weight. Now about the bleeding episode, the corpus luteum produces progesterone in the second half of the cycle to maintain the endometrium. In PCOD, as the hormonal milieu inside the ovary is disturbed by raised androgens from the stroma of the ovary (hyperplasia of the stroma is seen in PCOD), the quality of corpus luteum is not good, so the luteal phase support is bad (also a reason for PCOD ladies needing hormonal support during the initial pregnancy period, to avoid early miscarriage). So the endometrium will not be strong enough to stay on till periods, so you will get bleeding on and off, with or without clots, fleshy masses. Primolut-N (norethisterone) is to supplement this progesterone support. Usually, bleeding occurs after seven to ten days of Primolut-N. If you still do not bleed, it only means the initial priming of the endometrium with estrogen has not been done, which is seen in PCOD. Only such an estrogen-primed endometrium will respond to progesterone. Then you will need any of the birth control pills twice a day for ten days.

I hope you find it helpful.

Kind regards.