HomeAnswersRheumatologyrheumatoid arthritisHow to help my wife who is having high ESR, RA factor, and swollen fingers?

My wife has rheumatoid arthritis with high ESR, RA factor and swollen fingers. Please suggest a solution.

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The following is an actual conversation between an iCliniq user and a doctor that has been reviewed and published as a Premium Q&A.

Medically reviewed by

Dr. Vinodhini J.

Published At June 2, 2020
Reviewed AtJuly 18, 2023

Patient's Query

Hello doctor,

I want a good rheumatologist for my wife who has been diagnosed with rheumatoid arthritis. She has got RA factor 150 and no other problems in blood reports. Anti-CCP is negative. She has swollen fingers both in her hands and legs. She is currently on Shellcal 500 and D joint capsules.

Hi,

Welcome to icliniq.com.

I have gone through the reports (attachment removed to protect patient identity). There is a high ESR (erythrocyte sedimentation rate), RA factor. I would like to take a few more details on the history part. But it would be better if someone can examine the joints as it is a long treatment that the patient will need. So she should be examined properly before commencing the drugs for it. Does she have early morning stiffness? Are there any dry eyes, dry mouth, or oral ulcers? Does any hair fall? Any other medications for diabetes or thyroid is she taking?

Thank you.

Patient's Query

Thank you doctor,

Morning stiffness and dry mouth are there. No oral ulcer, no hair fall, no diabetes, no thyroid and no medication.

Hello,

Welcome back to icliniq.com.

With your history and reports, one thing I want to be certain is that we are not dealing with some other condition which is known as Sjogren's syndrome. Sjogren's syndrome can have high ESR and rheumatoid factor positive along with joint pains, swelling, and fatigue. Only thing not favoring rheumatoid arthritis is the normal CRP (C-reactive protein) despite of so much inflammation. Anti CCP can be negative in few individuals. So I would suggest you get this test done which is pending. ANA (IFA method) and ENA (extractable nuclear antigen) qualitative. That should complete our work up.

As for medications, the safest bet we can start is tablet Hydroxychloroquine 200 mg twice daily. To start stronger medications for RA, we will plan after this test.

Same symptoms don't mean you have the same problem. Consult a doctor now!

Dr. Naval Mendiratta
Dr. Naval Mendiratta

Rheumatology

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