Heart & Circulatory Health

Bisoprolol (Concor) - Uses, Dosage and Side Effects

Written by
Dr. Sneha Kannan
and medically reviewed by Dr. Rishu

Published on Sep 09, 2019 and last reviewed on Oct 03, 2019   -  4 min read

Abstract

Abstract

Bisoprolol is a drug used to treat high blood pressure, which in turn reduce the risk of heart and kidney diseases. Read the article to know more.

 Bisoprolol (Concor) - Uses, Dosage and Side Effects

What Is Bisoprolol?

Bisoprolol is a drug that belongs to a group called beta-blockers. These medicines affect the blood flow through arteries and veins by blocking the action of epinephrine on the heart and blood vessels. It is used to treat hypertension and heart failure, as it lowers blood pressure and prevents heart attacks, stroke, and kidney diseases. It comes as a tablet, and only available on prescription.

Bisoprolol is well-tolerated because it is a cardioselective β1-adrenergic blocking agent and is a useful alternative to non-selective β-blocker drugs like Carvedilol and Labetalol. It can be used alone or in combination with other drugs and is useful in patients with chronic obstructive pulmonary disease (COPD).

What Is Bisoprolol Used For?

It is used to treat hypertension and heart failure. Lowering blood pressure prevents heart attacks, strokes, and kidney problems. Apart from high blood pressure, Bisoprolol is also used to treat atrial fibrillation and prevent chest pain due to angina.

How Does Bisoprolol Work?

Bisoprolol works by enhancing the heart’s ability to relax. It makes the heart beat slower and less forcefully. This relaxes the arteries and veins and reduces blood pressure and relieves irregular heart rhythms.

Bisoprolol blocks the adrenalin stimulation of beta receptors found in the heart muscle cells and heart conduction tissue. Usually, adrenalin and noradrenalin stimulation by beta receptors result in contraction of heart muscles and blood vessels, which increases the heart rate and blood pressure. Bisoprolol blocks this action, which makes the heart to contract slowly and lowers heart rate and blood pressure.

What Is the Dosage of Bisoprolol?

Bisoprolol tablets are available in 5 mg and 10 mg strengths. Always take any tablet as prescribed by your doctor. Do not alter the dosage, unless suggested by your doctor. The dosage is:

  • For hypertension - 2.5 to 5 mg orally once a day, can increase up to 10 or 20 mg per day if necessary.

  • For heart failure - 1.25 mg orally once a day, can increase gradually not more than 10 mg per day.

For people suffering from asthma or any respiratory problems, kidney and liver problems, your doctor will prescribe 2.5 mg of Bisoprolol and then increase the dose gradually if needed.

What Are the Precautions and Contraindications of Bisoprolol?

Tell your doctor if you have the following health conditions, as it is not safe to use Bisoprolol:

How to Take Bisoprolol?

Always take this medicine as it was prescribed by your doctor. Read the prescription label and follow the directions properly. Go for regular checkups, as your doctor might change the dosage depending on how you respond to the medicine. Avoid using it in a larger or smaller dosage than prescribed.

Never stop taking the drug abruptly, as it might worsen your condition or cause other serious heart problems. Keep taking medicine even after the symptoms of high blood pressure go away, as you may need to use this for the rest of your life.

What Are the Symptoms of Bisoprolol Overdose?

If you take more than the prescribed dosage of Bisoprolol, it might lead to overdose. The symptoms of overdose are:

  • Blurred vision.

  • Cold sweats.

  • Dizziness.

  • Confusion.

  • Tremors.

  • Fast heartbeat.

  • Pale skin.

  • Coma.

  • Confusion.

  • Less urine output.

  • Difficulty breathing.

What Are the Side Effects of Bisoprolol?

The common side effects include:

  • Slow heart rate.

  • Dizziness.

  • Diarrhea.

  • Nausea.

  • Insomnia.

  • Joint pain.

  • Cough.

  • Dry mouth.

  • Stomach pain.

  • Headache.

  • Altered libido.

  • Flu-like symptoms.

These symptoms are usually mild and resolve on their own in a few days. But get immediate medical help, if your symptoms are getting worse or if you are not feeling fine even after a few days.

The serious side effects include:

  • Allergy - skin rash, hives, facial swelling, difficulty to swallow, and itching.

  • Irregular heart rate.

  • Dizziness.

  • Hypotension.

  • Lowers HDL (high-density lipoprotein).

  • Masks the symptoms of diabetes.

  • Increases insulin resistance.

  • Worsens congestive heart failure.

  • Increases triglyceride levels.

  • Lightheadedness.

  • Dyspnea.

  • Chest pain.

  • Leg and ankle swelling.

  • Numbness and tingling sensation in hands and feet.

  • Muscle pain.

  • Tremors.

  • Profuse sweating.

  • Confusion.

Go to the emergency room immediately if you notice any of these serious side effects.

What Other Drugs Can Bisoprolol Interact With?

This medicine can interact with other medications and can change the way that drug works. It can prevent the drug from working properly or result in severe side effects. Inform your doctor if you are taking any of the following medicines:

  • Heart rhythm drugs - Sotalol, Amiodarone, Moricizine, Digoxin.

  • Beta-blockers - Atenolol, Metoprolol, Propranolol.

  • Calcium channel blockers - Amlodipine, Nifedipine.

  • Diltiazem.

  • Clonidine.

  • Reserpine.

  • Guanethidine.

  • Blood pressure drugs.

  • Alpha-blockers - Doxazosin, Prazosin.

  • Lidocaine.

  • Antimalarial drugs - Mefloquine.

  • Norepinephrine or Phenylephrine.

  • Nonsteroidal anti-inflammatory drugs (NSAIDs) - Indomethacin, Naproxen.

Do not consume alcohol while taking Bisoprolol, as it can dangerously lower your blood pressure levels. For more information on this drug and other ways to lower your blood pressure, consult a cardiologist online now.

Last reviewed at:
03 Oct 2019  -  4 min read

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