Women's Health Data Verified

I-Pill Versus Unwanted 72 - Side Effects, Precautions and Usage

Published on May 17, 2022   -  7 min read


I-pill and Unwanted 72 are the emergency contraceptive pills used frequently by women as they help them to avoid pregnancy. Read the article to learn more.


What Are Emergency Contraceptive Pills (ECPs)?

As the name suggests, emergency contraceptive pills are used by women after intercourse to prevent pregnancy. It does not mean that these pills are used every time to stop the pregnancy. They are only used after unprotected intercourse. Sometimes, these pills are also known as “morning-after pills” or “the day after pill,” because these medications need to be taken immediately after intercourse. It is because the earlier the pills are taken, the better the effect. If the woman consumes these pills within 72 hours of unprotected intercourse, they provide up to 95 to 98 % protection from unwanted pregnancy. However, these pills must not be used if the patient is sexually active and wants to avoid pregnancy. These pills are of great help in avoiding pregnancy after rape or forced sex. However, the doctor should be consulted before these pills are used.

What Is Unwanted 72?

Unwanted 72 comes under the category of emergency contraceptive pills. They are named so because they have to be taken within 72 hours of unprotected sex to prevent unplanned pregnancy. Unwanted 72 pills contain levonorgestrel, which is a hormone and is used for emergency contraception. The patient needs to make sure that the pill is taken at the earliest to obtain the best results. It is because the pill is not very effective if taken after 72 hours or later. Unwanted 72 needs to be taken orally with a glass of water. Nausea, vomiting, headache, tiredness, and abdominal pain are some of the side effects of this medication. These side effects usually subside after some time, but the patient must consult the doctor if the side effects persist.

What Is an I-pill?

I-pill is also used as an emergency contraceptive drug to prevent unplanned pregnancy. However, one must remember that I-pill is not a birth control medication that can be used at any time. Rather, it is an emergency drug and needs to be used only after unnatural sex, rape, or forced sex. It is because these are the situations where the woman does not want to have a baby, but she might get pregnant due to unwanted intercourse. The I-pill also contains levonorgestrel which works to prevent the production of eggs from the ovaries (female reproductive system). I-pill is only meant for women under 25 to 45 years of age and must not be consumed by teenagers.

What Is the Composition of I-pill and Unwanted 72?

Both I-pill and Unwanted 72 contain the hormone levonorgestrel as the principal ingredient. However, I-pill also contains ethinylestradiol in small amounts. The composition of I-pill and Unwanted 72 is described below:

  1. Levonorgestrel - Levonorgestrel or progestin is a hormone present in emergency contraceptive pills. An emergency contraceptive pill contains about 1.5 milligrams of levonorgestrel. The patient must consume the medication at the earliest to achieve the best results.

  2. Ethinylestradiol - Ethinylestradiol or synthetic estrogen is used in combination with levonorgestrel in emergency contraceptive pills. The I-pill contains about 0.03 milligrams of ethinylestradiol. It works by preventing the development of eggs and helps to stop unplanned pregnancy.

What Is the Mechanism of Action of the I-pill?

Ovaries are one of the most crucial organs of the female reproductive system. Under normal conditions, the ovaries produce eggs every month at the time of menstruation. The ovaries are also responsible for the production of female sex hormones, known as progesterone. When the female is ready for conception, the ovaries increase the production of progesterone so that the uterus is ready for a future pregnancy. Next comes the process of fertilization. Suppose the female receives the sperm from the male during intercourse; the eggs and the sperm mix together to give rise to an embryo (future baby). However, if the pregnancy does not occur, the progesterone levels fall, and the menstrual cycle begins. There are two mechanisms by which I-pill works, depending upon whether the menstrual cycle is going on or not:

  1. As I-pill contains levonorgestrel, the progesterone levels of the body will be elevated. So, the ovaries get a message that they need to stop producing eggs as the progesterone levels are high.

  2. If the ovaries have released the egg before the consumption of the drug, I-pill inhibits the procedure of fertilization.

What Is the Mechanism of Action of Unwanted 72?

The human body contains a pituitary gland that produces two hormones, mainly follicle-stimulating hormone (FSH) and luteinizing hormone (LH). These hormones are also known as gonadotropins because they control the function of the male and female reproductive organs (gonads). In females, the follicle-stimulating hormone (FSH) and luteinizing hormone (LH) control ovulation and the menstrual cycle. As Unwanted 72 contains levonorgestrel in high amounts compared to I-pill, the follicle-stimulating hormone (FSH) and luteinizing hormone (LH) get inactivated. As a result, the lining of the uterus becomes thin, making the process of implantation almost impossible. So, Unwanted 72 is used to prevent pregnancy after intercourse. The patient needs to remember that the drug does not work if the patient is already pregnant. Also, the woman must take the drug within 72 hours to get the best results.

What Are the Indications of Emergency Contraceptive Pills (I-pill and Unwanted 72)?

The main goal of emergency contraceptive pills like I-pill and Unwanted 72 is to prevent unplanned pregnancy. The uses of I-pill and Unwanted 72 are listed below:

  1. Unprotected intercourse.

  2. Rape or sexual assault.

  3. If the condom breaks or tears during the intercourse, the patient might need to consume the emergency contraceptive pill.

  4. If the patient missed his regular birth control pill, Unwanted 72 or I-pill needs to be taken to stop the unwanted pregnancy.

What Are the Side Effects of I-pill and Unwanted 72?

The emergency contraceptive pills like I-pill and Unwanted 72 interfere with the normal mechanism of the body, so the patient might present with some side effects. The side effects of these medications are listed below:

What Precautions Must Be Taken Before Using I-pill and Unwanted 72?

I-pill and Unwanted 72 come with a list of precautions that need to be taken by the patients before using them. The patient must take the following precautions:

  1. Both the drugs need to be stored in a cool and dry place.

  2. The drugs are only meant to be used for emergency purposes, so the patient must not consider them regular contraceptive pills.

  3. Consult the doctor before taking these drugs.

  4. Keep the medication away from the reach of children.

  5. Avoid keeping them in a refrigerator or a moist place.

  6. The drugs do not provide any protection from sexually transmitted diseases, so the person must wear a condom before intercourse.

  7. Females who are pregnant or expecting to be must not take these drugs.

What Are the Drug Usage Warnings Associated With I-pill and Unwanted 72?

The patient must consume these drugs only after consultation with the doctor. Do not take the emergency contraceptive drugs under the following circumstances:

Which Drugs Interfere With the Working of I-pill and Unwanted 72?

The doctor always asks the patient about his drug history before recommending emergency contraceptive pills. It is because the effectiveness of these pills gets reduced if other drugs are taken along with them. The following drugs reduce the effectiveness of emergency contraceptive pills:

  1. Phenytoin.

  2. Carbamazepine.

  3. Griseofulvin.

  4. Felbamate.

  5. Topiramate.

  6. Rifampicin.

  7. Tetracycline.

  8. Primidone.

  9. Benzodiazepines.

  10. Corticosteroids.

  11. Beta-blockers.

Which One Is Better- I-pill or Unwanted 72?

The answer to this question depends upon the expectation of the person from the medication. The following points compare the two drugs:


I-pill and Unwanted 72 come under the emergency contraceptive drugs that aim to prevent unplanned pregnancy after unnatural intercourse. These drugs must be consumed at the earliest to get the best results. There is no major difference in the composition of I-pill, and Unwanted 72, as both of them contain synthetic progesterone. However, I-pill is considered more effective than Unwanted 72 as it contains more progesterone. People consuming any of these drugs must remember that they are not regular birth control pills and have to be used only in emergencies. However, the patient must consult a doctor before taking these drugs to know about the benefits and the side effects.

Article Resources

Last reviewed at:
17 May 2022  -  7 min read




Comprehensive Medical Second Opinion.Submit your Case

Related Questions & Answers

After I-pill, I had a flow but it was not heavy. What is the chance of pregnancy?

Query: Hello doctor, I need an urgent help. I was on my fifth day of my periods and I made out with my partner. I had my pants and my panty on and he had his penis out. He ejaculated on my pant, and I saw that some portion of my panty was wet as well. And I felt wet in the skin of the lower portion of abd...  Read Full »

Will I-pill tablet work if taken two hours after the act?

Query: Hello doctor, My wife is 25 years old and she had her period on the 14th of last month. On the 1st of this month, while having intercourse, unfortunately, the condom broke. She had taken I-pill within two hours. Can you please advise if the tablet will work or not?  Read Full »

Took unwanted 72 after having an unprotected sex. Will I be pregnant?

Query: Dear Doctor, I had unprotected sex. She took unwanted 72 within 12 hours. Will she be pregnant? In case she becomes pregnant, suggest any options other than abortion.  Read Full »

Popular Articles Most Popular Articles

Do you have a question on I-pill or Unwanted 72?

Ask a Doctor Online

* guaranteed answer within 4 hours.

Disclaimer: No content published on this website is intended to be a substitute for professional medical diagnosis, advice or treatment by a trained physician. Seek advice from your physician or other qualified healthcare providers with questions you may have regarding your symptoms and medical condition for a complete medical diagnosis. Do not delay or disregard seeking professional medical advice because of something you have read on this website. Read our Editorial Process to know how we create content for health articles and queries.