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A Patient's Guide to Recurrent Cellulitis

Published on Mar 04, 2019 and last reviewed on Feb 03, 2023   -  4 min read


Cellulitis is a bacterial infection of the deep layer of the skin and it recurs frequently. Read this article to know more.

A Patient's Guide to Recurrent Cellulitis


Cellulitis is an inflammatory condition of the skin characterized by swelling, pain, and discoloration. It is believed to be a bacterial infection affecting the deeper tissues of the skin. Cellulitis can affect hands, feet, legs, eyes, etc. Cellulitis is bound to recur frequently. There are various medical conditions responsible for recurrent cellulitis. It has to be treated at the earliest. Any delay in the treatment can increase the risk of complications like the spreading of the infection to different parts of the body.

Cellulitis is generally managed with oral antibiotics. A doctor will prescribe medications (antibiotics) for about seven to ten days. Since cellulitis is prone to recur, doctors usually put the patient on low-dose antibiotics for a longer time to keep the recurrent infection in check.

What Are the Various Causes of Recurrent Cellulitis?

The following are the various causes of recurrent cellulitis -

1) Chronic Leg Swelling:

Venous insufficiency, lymphedema, congestive heart failure, liver disease, and kidney disease are all causes of chronic leg swelling that predispose you to recurrent cellulitis. Keep your legs elevated to minimize swelling. For venous insufficiency and lymphedema, compression stockings can be used to reduce the swelling of your legs. For swelling caused by heart, liver, or kidney disease, you may require diuretics (water pills) to help your body eliminate excess salt and water to decrease swelling.

2) Fungal Infections:

Fungal skin infections such as athlete's foot can predispose you to recurrent cellulitis. These fungal infections provide a portal of entry for bacteria, most often streptococci and staphylococci, by causing cracks in the skin. Check your feet, especially between the toes, for cracks in the skin and a scaly rash. This might be an athlete's foot. You need to clean your feet diligently every day and you may require a topical antifungal medication to treat the fungal infection. Fungus likes to grow in a moist environment, so it is important to keep your feet free of excessive sweat and moisture.

3) Peripheral Arterial Disease:

If the blood flow to your legs is impaired, you are at higher risk of developing cellulitis. Your blood carries white blood cells and antibiotics to the site of infection. Without good blood flow, your body's immune system and medications cannot reach the affected area very well. You may require computed tomography (CT) scan to evaluate the blood flow and if the results are abnormal, you may need to see a vascular surgeon and discuss interventions to improve the blood flow. Ask your doctor to check the pulses on your feet to ensure they can be felt.

4) Obesity:

Obesity is associated with chronic leg swelling and serves as an indirect risk factor for cellulitis. Talk to your doctor about strategies to lose weight. This generally includes diet and exercise. Sometimes, medications or bariatric surgery are required if you are unable to lose weight with lifestyle modifications. Obesity is associated with many other medical problems as well such as diabetes, high cholesterol, heart disease, and stroke. It is strongly recommended to maintain a healthy weight to reduce your risk of developing other chronic diseases.

5) Prior Episode of Cellulitis:

If you had cellulitis previously, you are at risk of getting it again in the same area because the infection causes lymphatic scarring and impaired lymphatic drainage, which leads to lymphedema. The risk of infection increases with the number of prior episodes of cellulitis.

6) Chronic Skin Conditions:

If you have eczema, dermatitis, or another skin problem, you are at higher risk of developing cellulitis because the skin is damaged by the underlying skin disease, or by scratching from itchiness. It is important to assess for any underlying skin disorder and ensure it is adequately treated to minimize your risk of infection. Sometimes, you may need to see a dermatologist for evaluation.

7) Antibiotic Prophylaxis:

Antibiotics can be used to treat and prevent cellulitis. If you get three to four episodes of cellulitis per year, then you may qualify for low-dose Penicillin prophylaxis. By taking this medication every day, you minimize the risk of recurrent infection. Penicillin is not meant to be taken for many years or lifelong. It is meant to give you time to address any predisposing risk factor for cellulitis. Once those risk factors have been eliminated or controlled, then your doctor should take you off Penicillin and monitor you closely for any recurrent infection.

8) Cellulitis Mimickers:

There are some conditions that can mimic cellulitis such as venous insufficiency, blood clot, gout, and dermatitis. If your condition is not improving on antibiotics, then ask your doctor if the diagnosis is correct and if you are taking the right antibiotic. If the diagnosis is unclear or if the antibiotic is not working, then you should be referred to a dermatologist or infectious disease specialist. Do not keep taking different courses of antibiotics without a proper evaluation because this only delays the diagnosis and proper treatment.

What Are the Different Ways to Prevent Recurrent Cellulitis?

The following measures can be followed to prevent recurrent cellulitis.

  • It is advised to keep the skin clean and tidy. The skin has to be moisturized adequately to avoid dryness.

  • Proper footwear and clothing have to be worn in order to avoid any injuries or scratches (bacteria can enter the tissue site through a scratch or a cut).

  • Both the toenails and fingernails have to be cut and cleaned with proper care.

  • If there is any cut or scratch in the body, it has to be treated with medicine and a band-aid if needed.

  • Quitting smoking and giving up alcohol will help prevent recurrent cellulitis.


Cellulitis is a painful condition and if left untreated, can spread to other parts of the body. Thus, medical care at the earliest is mandatory. But recurrent infections can make life a little tough. Thus, proper precautions have to be taken to keep the recurrent infection in check.

Frequently Asked Questions


What Should a Patient Do in Case of Recurring Cellulitis?

Cellulitis is a bacterial skin infection wherein the patient experiences swelling, tenderness, pain, and redness. Hence, to prevent recurrent or repeated episodes of cellulitis, the patient must keep his skin clean, hydrated, or moisturized. In addition, one must cover his skin properly with appropriate clothes and use gloves whenever required.


Why Does Cellulitis Recur?

Cellulitis is an infectious disease of the skin that tends to recur due to numerous factors. Some factors that increase the risk of cellulitis are listed below:
- Dermatologic conditions like athlete’s foot.
- Animal or insect bites.
- Pressure sores.
- Surgical incisions.
- Immunological problems like diabetes.
- Peripheral artery disease (a condition wherein the arteries become narrow, resulting in reduced blood supply to the arms or legs).
- Swelling or edema of the legs.


What Is the Treatment of Chronic Cellulitis?

Cellulitis is a bacterial disease, so it needs to be treated with antibiotics soon to prevent a recurrence. The treatment mainly involves oral antibiotics like Cephalexin or Dicloxacillin. In addition, compression, elevation, non-steroidal anti-inflammatory drugs like Ibuprofen and Naproxen, or the use of compression stockings can be of great help in overcoming cellulitis.


Is Recurrent Cellulitis a Serious Condition?

People tend to get recurrent cellulitis even after undergoing suitable treatments. The incidence rate of recurrent cellulitis is 16 to 53 %. Recurrent cellulitis can cause swelling of the affected limb and interfere with the lymphatic drainage system.


Can a Patient Get Rid of Cellulitis Permanently?

Cellulitis is curable, and the patient can get cured permanently. Patients who receive proper treatment on time recover completely with antibiotics. The small patches seen in cellulitis usually subside within five to seven days. However, the duration of healing depends on the patient’s general health. Some patients take several weeks to recover fully.


How to Get Rid of Cellulitis Quickly?

The treatment for cellulitis depends on the severity of the condition. Though antibiotics can be taken orally to address the underlying condition, some home remedies like applying a warm compress, elevation, keeping the skin dry, and using antibiotic ointments can help one get rid quickly.


Can Improper Hygiene Cause Cellulitis?

Cellulitis is a severe skin infection that occurs due to numerous factors, including inadequate hygiene. Studies report that most cases of cellulitis are reported around damaged skin. Hence, one must maintain adequate hygiene and wash hands with soap to prevent infections.


Should a Patient With Cellulitis Drink Plenty of Water?

It is important for patients with cellulitis to stay hydrated adequately. Water does not help one to recover from cellulitis directly, but it helps prevent dehydration which might exacerbate cellulitis.


What Should a Patient Do if Antibiotics Fail to Treat Cellulitis?

Antibiotics are the first line of therapy against cellulitis. However, the symptoms of cellulitis might worsen over time, and it might spread rapidly, resulting in serious complications. Hence, if cellulitis does not subside even after taking antibiotics, the patient must visit the doctor or emergency room for an adequate diagnosis.


What Symptoms Would a Patient Have if Cellulitis Worsens?

Patients with severe cellulitis tend to have the following symptoms:
- High-grade fever.
- Fast heartbeat.
- The patient can become dizzy.
- Presence of purple patches on the skin.
- Disorientation.
- Confusion.
- Clammy or pale skin.
- Loss of consciousness.


Which Ointment Can Be Used for Cellulitis?

Oral antibiotics, including Cephalexin, and Trimethoprim, are the treatment of choice for cellulitis. However, the patient can apply Mupirocin ointment thrice daily, or products comprising 0.3 % retinol can be used to improve the appearance of the skin. The patient must apply the cream for five to six months.


Does Diabetes Affect Cellulitis?

Diabetes is one of the significant risk factors for cellulitis because high blood glucose levels hamper the functioning of the immune system resulting in the invasion of pathogenic organisms and delayed wound healing.

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Last reviewed at:
03 Feb 2023  -  4 min read




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