Q. My p24 antigen, HIV 1 and 2 antibodies, and tridot tests are negative. Do I need further tests?

Answered by
Dr. Ravinder K. Sachdeva
and medically reviewed by Dr. Hemalatha
This is a premium question & answer published on Dec 10, 2020

Hello doctor,

I had protected exposure followed by P24 antigen after 33 days, fourth-generation P24 Ag, HIV 1 and 2 antibodies (CMIA) after 38 days, and then tridot after 93 days. All reports were negative for all the tests. As all the reports are negative and protected exposure, can my HIV status be treated as safe? Another fourth-generation rapid HIV test is just optional and not mandatory to evaluate my HIV status, right? It was done only because of my request and anxiety about the authenticity of labs and tests. Even if I do not take this test, my HIV is negative based upon the result of the above tests, right? Or is it mandatory to take a fourth-generation rapid HIV test as per your prescription?



Welcome to

The answers to your queries are:

As you mentioned that it was protected sex, and there was no break or slippage of the condom. The risk of acquisition of HIV in this scenario is non-existent. It is great that your HIV test report at both time points is negative. If there had been no further exposure, your result would be considered conclusive, and there is no need to further repeating the test. HIV fourth-generation test mentioned after the last discussion is optional.

Please revert if any other information is required.

Thank you doctor,

I have a sore throat for the last four to five days. No fever or any other symptoms. The tests after 30 and 90 days are all negative. Can the sore throat after more than 100 days of exposure be a symptom of HIV?



Welcome back to

HIV is unlikely if there is no further unprotected exposure.

Was this answer helpful?


Same symptoms doesn’t mean you have the same problem. Consult a doctor now!

Related Questions:
Can exposure to pre-seminal fluid cause HIV?

I took an RNA HIV test 16 days after that exposure ... After 48 days, I took a fourth generation HIV test antibody/antigen ...   Read full

Are ELFA and HIV DUO tests conclusive at three and six months post-exposure?

 Can there be any point where both antibodies and p24 antigen are not detectable in an HIV infected patient ... Your last screening tests for HIV (human immunodeficiency virus), that is, fourth ...   Read full

Please explain about the CMIA test for HIV testing.

.. the specific answers for your questions. CMIA is based on chemiluminescence principle and it is performed on an automated analyzer. It is the most effective technique nowadays to rule out HIV. CMIA can almost 100 % rule out HIV after 90 days of e...   Read full

Also Read Answers From:

ideaComprehensive Medical Second Opinion.Submit your Case

Also Read

Coronavirus Variant Arcturus: | Omicron XBB.1.16 Variant
Arcturus is an emerging variant of the Omicron virus that causes various symptoms and spreads rapidly across the world. ...  Read more»
Adrenaline Rush - Symptoms, Causes, Effects, and How to Control
Adrenaline is a hormone responsible for fight or flight response. It is also a neurotransmitter and medicine. It is also...  Read more»
Fatty Liver - Types, Symptoms, Stages, and Treatment
The liver is the largest gland in the body. Its primary function is to process the food and drinks we consume. and filte...  Read more»

Ask your health query to a doctor online?

Ask a HIV AIDS Specialist Now

* guaranteed answer within 4 hours.

Disclaimer: No content published on this website is intended to be a substitute for professional medical diagnosis, advice or treatment by a trained physician. Seek advice from your physician or other qualified healthcare providers with questions you may have regarding your symptoms and medical condition for a complete medical diagnosis. Do not delay or disregard seeking professional medical advice because of something you have read on this website. Read our Editorial Process to know how we create content for health articles and queries.