P24 is a capsid structural protein that makes a protein shell on the surface of the HIV (human immunodeficiency virus). It helps in identifying the actual HIV particles present in the blood. They show a positive result when the test is taken after two to three weeks of HIV infection. P24 protein cannot be detected after a week of HIV infection as the virus takes some time to get multiplied. It is again undetectable when sufficient antibodies to HIV are produced. At this point, the standard HIV antibody test shows a positive result. Later in the course of HIV, it becomes detectable.
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I had unprotected intercourse with a girl. Why do I have leg pain and mouth sores despite testing negative for HIV?
Query: Hello doctor, I had intercourse with a girl two months back without safety measures. After one month I took a PCR test and it got negative. After 40 days I took a test for the p24 antigen and it got negative. Then after 56 days again, I took a PCR test and it was negative. My symptoms started with d... Read Full »
Answer: Hello, Welcome to icliniq.com. Thank you for your query. The chances of transmission of HIV by single unprotected intercourse are low. The HIV antibodies and PCR tests are negative. The chances of HIV tests becoming positive later is almost nil. But it is better to go for an HIV antibodies test afte... Read Full »
Do anti-human immunodeficiency virus tests check only for the antigen or also for antibodies?
Query: Hi doctor, I had a protected relationship with a girl but there was strong unprotected oral sex. I inserted my fingers into the her vagina for two minutes or more. This was the first time in my life that I had sex. There was a panic attack and I also started to fear human immuno deficiency virus. I ... Read Full »
Answer: Hi, Welcome to icliniq.com. Thank you for your query, The test detects both human immuno deficiency virus IV antigen and antibodies. The test result is conclusive at the specified dates. If there are no additional risk exposures, there is no need for additional human immunodeficiency virus tests. Read Full »
I tested negative for HIV 1/2 combo with a P24 antigen test after having an unprotected oral sex with a sex worker. Should I get PEP?
Query: Hi doctor,I am a 29-year-old male who got an unprotected blowjob from a sex worker at a massage parlor. I do not know her HIV (human immunodeficiency virus) status, I did oral sex only one time and I did not ejaculate in her mouth. Then she cleaned all with a towel and I washed my penis with soap an... Read Full »
Answer: Hi, Welcome to icliniq.com. The chances of transmission of HIV (human immunodeficiency virus) by single unprotected oral sex is almost nil unless there are bleeding wounds in the oral cavity. If the person is HIV-negative then there is no chance of transmission of HIV. The HIV antibodies negative... Read Full »
What kind of muscle pain is associated with ARS?
Query: Hi, I am a 31 year old male. About 38 days before I had sex with a CSW (Commercial Social Worker). It was protected vaginal sex and protected oral sex. Also there were deep throat kisses which lasted almost a minute. I am not sure if the condom was torn during the intercourse. Since last 3 weeks ... Read Full »
Answer: Hi, Welcome to icliniq.com. Based upon your history, my answer to your questions: 1. Are My Symptoms Related to ARS? Acute Retroviral Syndrome (ARS) typically begins 7-14 days after the exposure to a HIV positive patient, and may last for up to 3-4 months. The symptoms are typically "flu-like" w... Read Full »
I took the HIV combo test on the 32nd day after exposure. Is it a fourth-generation test?
Query: Hi doctor, I took the HIV-1, HIV-2, and p24 tests on the 32nd day after exposure. I am attaching the file. I want to know whether this is a fourth generation test. If yes, what are the chances that a fourth-generation test is negative on the 32nd day and will turn positive after the 45th day? Read Full »
Answer: Hi, Welcome to icliniq.com. The answers to your queries are: The test which has been performed is a fourth-generation test. This test looks for HIV (human immunodeficiency virus) antigens and antibodies. The test result (attachment removed to protect the patient's identity) is negative. If this... Read Full »
I had unprotected sex with my neighbor. I am afraid of HIV. Please help me.
Query: Hello doctor, I had unprotected sex with my neighbor. I am really afraid of HIV. Please help me. Read Full »
Answer: Hello, Welcome to icliniq.com. I read your query and understand your concerns. Please scan your reports and attach it while posting the follow-up query. Read Full »
Are immunochromatography test results after 28 days of exposure conclusive?
Query: Hello doctor, I have had HIV 1 and 2 antibody test to detect antigens p24, Gp41, and Gp120 of HIV immunochromatography after 28 days of unprotected vaginal sex, and the results are nonreactive. Does it mean I am safe from the virus? I am now two months past, and I have no symptoms. Read Full »
Answer: Hello, Welcome to icliniq.com. This HIV (human immunodeficiency virus) screening test involves antibodies and antigens accurately. It detects the majority of those infected at four weeks, whereas its sensitivity increases between 99 and 99.9 % at six weeks. So most HIV specialists consider ... Read Full »
I have some concerns. Do HIV combo test detect p24 antigen for HIV-2?
Query: Hello doctor, I have some concerns regarding HIV testing. Please answer my questions below regarding the same. Does HIV combo test detect p24 antigen for HIV-2? Do combo tests and antibody tests detect all subtypes and strains of HIV? Can a PCR test detect all subtypes of HIV? Thank you. Read Full »
Dr. Goswami Parth Rajendragiri
Answer: Hello, Welcome to icliniq.com. Thanks for writing in, and I understand your concern. Based on your attached report (attachments removed to protect the patient's identity) of the human immunodeficiency virus (HIV) combo test, it can detect both 1 and 2 types of HIV virus. As I can see, it is a nega... Read Full »
Are the tests which I have undergone sufficient to conclude my HIV status?
Query: Hi doctor, I had protected sex with a CSW five months before. I do not know the condom's status, either broken or ruptured. I was drunk that day, but I did not even ejaculate. Since I had a doubt, I took a test in the 4th week, HIV 1 and 2 antibody rapid tests from the laboratory, which was non-reac... Read Full »
Answer: Hi, Welcome to icliniq.com. I can understand your concern. You have gone for antibody testing for HIV 1 and 2 many times, and it has come negative. When two tests for antibody detection based on different principles are negative, it means the individual is not having an HIV infection. You h... Read Full »
I had gay encounters followed by a lot of bleeding. Can it be AIDS?
Query: Hello doctor,I am a 32-year-old man. I had gay encounters with three men in a massage parlor on three different days. In all three cases, we have used condoms. In my second and third encounters, I got a lot of blood, and that too very dark-colored blood, and something else also came. I had a word wi... Read Full »
Answer: Hello, Welcome to icliniq.com. I read your query and understand your concerns. First of all, I like to inform you that the transmission of HIV (human immunodeficiency virus) requires the mixing of body fluids. The use of condoms effectively prevents such mixing. I understand that there was bleedi... Read Full »