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Ulcerative colitis (UC) is a type of inflammatory bowel disease (IBD), which is a group of disease that affects the digestive tract. Ulcerative colitis results from inflammation of the lining of the colon or rectum or both. This inflammation results in constant and rapid bowel movement. It also produces ulcers in the lining of the colon, which can involve the entire colon or large intestine. The formation of ulcer causes discharge of pus, mucus, and blood in stools. Some of the symptoms seen are stomach pain, diarrhea, rectal pain, weight loss, and malnutrition. Medications like Sulfasalazine, Mesalamine, Balsalazide, Olsalazine, and biologics are used in its treatment.