Carpal tunnel syndrome is a condition in which there is tingling, weakness, and numbness in the hands and arms due to compression of nerves in the carpal tunnel, which is a narrow canal on the palm side of the wrist. Any fracture, inflammation, or injury that irritates the median nerve in the carpal tunnel can cause this syndrome. This syndrome more commonly affects women than men. You can prevent carpal tunnel syndrome by relaxing your grip, stretch and bend your wrist periodically, use a comfortable computer mouse while working, and by keeping your hand warm. Nonsurgical treatment includes wrist splinting, anti-inflammatory drugs, and corticosteroids.