A bone biopsy is a technique in which bone specimens are extracted to discover if cancer or additional abnormal cells are present. A bone biopsy simulates the external layers of bone, and a bone marrow biopsy implicates the innermost portion of the bone. It is of two types: open biopsy and needle biopsy.
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The reports of bone marrow aspiration and biopsy differ. How?
Query: Hi doctor,Bone marrow aspiration twice showed hypercellular bone marrow with overgrowth of WBC and megakaryocytes with all stages of maturing including micromegakaryocytes. But at the same time, the second BMA during bone marrow biopsy showed normocellular bone marrow. Is something like that possibl... Read Full »
Dr. Goswami Parth Rajendragiri
Answer: Hi, Welcome to icliniq.com. You have not mentioned the age of the patient, peripheral smear, and CBC (complete blood count) findings. You have mentioned that bone marrow was showing overgrowth of the WBC (white blood cells) and micromegakaryocytes. So, it is a myeloproliferative condition. ... Read Full »
Can multiple myeloma be diagnosed only by doing blood tests and X-rays?
Query: Hi doctor, I am a 63 year old male. I have been recently diagnosed with multiple myeloma. My doctor, who is listed as a hematologist or oncologist, said that I must undergo chemotherapy asap. His diagnosis was based solely on bloodwork and a full skeletal x-ray. There was no MRI or PET scan or bone... Read Full »
Answer: Hi, Welcome to icliniq.com. Blood work can strongly suggest myeloma; however, marrow biopsy is needed. But, one can fairly be sure about the diagnosis. Before starting treatment one will need the bone marrow biopsy. Also, bony lesion if visible on x-ray, then one may proceed without MRI or PET scan.... Read Full »
How long would I have to take antibiotics for P. acnes infection?
Query: Hi doctor, Four months before, I was diagnosed with P. acnes infection. It resulted from a shoulder stabilization 12 months earlier. I have had two surgeries for this. One to take the biopsies which diagnosed the infection and another to remove the sutures and clean out the shoulder joint. My surge... Read Full »
Answer: Hi, Welcome to icliniq.com. Your surgeon should have removed the anchors in your first surgery as they are possible contamination source. But, three months on antibiotics with no complete cure is too much time as most patients resolve in a few weeks. I suggest that you take another bone biopsy and c... Read Full »
What are the further investigations done to confirm IgM MGUS?
Query: Hi doctor, I am 46 years old and I was diagnosed with IgM MGUS at low concentration last month. I am worried about the bone marrow results coming next week. My GP referred me to a hematologist. I do not have the symptoms of WM but hematologists suggest a bone marrow biopsy and CT scan excludes lymp... Read Full »
Answer: Hi, Welcome to icliniq.com. Based on the reports, you have IgM MGUS (monoclonal gammopathy of undetermined significance). But we need to confirm it by doing a bone marrow biopsy and it should be less than 10 % clonal lymphoplasmacytic or plasma cells in the bone marrow. About one percent of people... Read Full »