Common "Disulfiram-like Reaction" queries answered by top doctors | iCliniq

Disulfiram-like Reaction

When taken along with alcohol, certain drugs can cause disulfiram-like reactions, meaning reactions in a person similar to those who take Disulfiram and consume alcohol. Such drugs include Metronidazole, Chloramphenicol, Furazolidone, and Quinacrine. The adverse reaction can include nausea, dizziness, flushing, abdominal pain, vomiting, headache, chest discomfort, etc.

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Is it safe to take tablet Metronidazole 5 hours after drinking alcohol?

Query: Hello Doctor, I took tablet Metronidazole 5 hours after I had taken 20 ml of red wine. What can I do now?  Read Full »


Dr. Sameer Kumar

Answer: Hi, Metronidazole and alcohol interaction causes disulfiram-like reaction. This leads to nausea, vomiting, tachycardia (increased heartbeat), shortness of breath, etc. If you had consumed red wine 5 hours before the drug intake, then it is all right. There is nothing much to fear. You may have nau...  Read Full »

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