Common "Overnight Dexamethasone Suppression Test" queries answered by top doctors | iCliniq

Overnight Dexamethasone Suppression Test

An overnight dexamethasone suppression test is done to check the action of dexamethasone on the production of cortisol hormone. Dexamethasone is a synthetic cortisol hormone. So, ideally, after the administration of dexamethasone, the body should release less amount of cortisol. It has two variants, namely low dose, and high dose. A low dose is given to diagnose Cushing's syndrome, whereas the high dose test is done in patients with Cushing's syndrome to detect tumors of the pituitary gland.

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All the answers published in this website are written by verified medical doctors, therapists and health experts. The Content has been moderated by iCliniq medical review team before publication. Post your medical clarifications on iCliniq by choosing the right specialty and get them answered. Your medical queries will be answered 24/7 by top doctors from iCliniq.

Why do I have a lot of health issues like bruising, hair fall, and weight gain?

Query: Hello doctor, I am a 43 year old female. My height is 5 feet 6 inches, and I weigh 185 lbs. I feel awful. Please tell me what you think may be wrong. Most of my adult life weight was 150 to 155 lbs. A sudden weight gain started five years ago. My weight is now always in the 175 to 185 range. I eat a...  Read Full »


Dr. Uphar Gupta

Answer: Hello, Welcome to icliniq.com. I have gone through your history, and commend you for the detailed presentation. You appear to be suffering from Cushing's syndrome. You have probably consumed steroids as a supplement or for pain relief. You have achieved menopause at an early age, but still, we...  Read Full »

Are my symptoms due to PCOS?

Query: Hi doctor, I am a 34 year old white female. My height is 5.4 feet and weight is 165 lbs. I am a healthy athlete (CrossFit athlete and a former state champion). I had a very high stress as entrepreneur for more than 5 years. My initial complaints were low energy, depression, fatigue, irregular, heavy...  Read Full »


Dr. Bindiya Thakkar

Answer: Hi, Welcome to icliniq.com. This is probably PCOS (polycystic ovarian syndrome) as you mentioned. Your history is consistent with it. I need the actual report of testosterone to know the method used for analysis and whether it was total or bioavailable testosterone. I noticed the liver function te...  Read Full »

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