Common "Depakote" queries answered by top doctors | iCliniq


Depakote, also called sodium valproate, is a mood stabilizer medication that works in the brain. It is used for manic depression (mania associated with bipolar disorder), epilepsy (seizures), and migraine headaches. It causes drowsiness, abdominal pain, nausea, diarrhea, low platelet count, vomiting, tremors, hair loss, and tiredness.

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All the answers published in this website are written by verified medical doctors, therapists and health experts. The Content has been moderated by iCliniq medical review team before publication. Post your medical clarifications on iCliniq by choosing the right specialty and get them answered. Your medical queries will be answered 24/7 by top doctors from iCliniq.

I have multiple mental health problems. Can I use Depakote?

Query: Hi doctor,I have been diagnosed with bipolar disorder, severe anxiety, PTSD, and OCD. I was taking 2 mg of Abilify in the morning for bipolar, Hydroxyzine for anxiety, and Mirtazapine for depression and insomnia. Hydroxyzine has been working wonders for my anxiety but I was still feeling locked up i...  Read Full »

Dr. Seikhoo Bishnui

Answer: Hi, Welcome to I understand your concern. Depakote is a mood stabilizer drug. The drug is a safe drug if used under proper prescription and in prescribed doses. I am using the drug on a lot of patients of mine and they are doing good. Yes, the drug is associated with common side effects...  Read Full »

I read Depakote and Paroxetine can cause Parkinson's. How to stop them without withdrawal symptoms?

Query: Hello doctor, I am suffering from OCD and doctor prescribed Depakote XR 500 mg and Paroxetine CR 25 mg, which I am taking for last eight years. I read that these medicines can cause drug-induced Parkinson's. Please advise how to stop taking these medicines without withdrawal symptoms.  Read Full »

Dr. Vishal Anilkumar Gandhi

Answer: Hello, Welcome to I do not think that those medications can induce Parkinson's. Antipsychotic drugs are more common to induce extrapyramidal symptoms like Parkinson's. Still, if you want to stop it, then you need to taper off over months gradually. It may lead to worsening your OCD.  Read Full »

I want to know about Valtoco's effectiveness in seizures.

Query: Hello doctor, I am a 29-year-old dealing with seizures for the past 10 years, especially during stress or anxiety. Currently on 750 mg of Depakote, I came across Valtoco and its benefits for seizures. How does it differ from Depakote, and how effective is it for stress or anxiety-induced seizures? S...  Read Full »

Dr. Vandana Andrews

Answer: Hi, Welcome to I read your query and can understand your concern. Valtoco (Levetiracetam) is an FDA-approved (Food and Drug Administration) antiepileptic medication for treating seizures (sudden, abnormal brain activity causing various symptoms) in adults with epilepsy (a neurological d...  Read Full »

Do I need liver supplements while taking Depakote?

Query: Hello doctor, Are there any liver supplements that I can take while on Risperdal and Depakote?  Read Full »

Dr. Surabhi

Answer: Hi, Welcome to The side effects of Depakote (Sodium valproate) on the liver are quite common and well known. It does cause an increase in liver enzymes level and symptoms like weakness, lethargy, jaundice (yellowing of skin and sclera), loss of appetite - all due to its effect on the ...  Read Full »

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