Common "P24 Antigen" queries answered by top doctors | iCliniq

P24 Antigen

P24 is a capsid structural protein that makes a protein shell on the surface of the HIV (human immunodeficiency virus). It helps in identifying the actual HIV particles present in the blood. They show a positive result when the test is taken after two to three weeks of HIV infection. P24 protein cannot be detected after a week of HIV infection as the virus takes some time to get multiplied. It is again undetectable when sufficient antibodies to HIV are produced. At this point, the standard HIV antibody test shows a positive result. Later in the course of HIV, it becomes detectable.

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Does the p24 antigen get detected after nine months of HIV infection without treatment?

Query: Hello doctor, I am concerned regarding p24 antigen detection. I read in different articles that it is delectable for only two months, and later it disappears as antibodies are formed. The antigen appears again if the person is not being treated. Is it like that? Does the p24 antigen level increase ...  Read Full »


Dr. Arun Kaushik. R

Answer: Hello, Welcome to icliniq.com. The p24 antigen can be detected faster than antibodies. After two months, as one produces antibodies, the virus will be killed, and the p24 might not be detectable. However, once the antibody level reduces in the body, the antigen can be detected as the viral l...  Read Full »

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