Anti-Aqp4 means antibodies to aquaporin-4 (NMO-IgG or AQP4-Ab), which consists of sensitive and high-specificity serum markers of optical neuromyelitis (the spinal cord and optic nerve are damaged by the immune system) and classic multiple sclerosis (shield which covers the nerves is damaged by the immune system).
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I tested for neuromyelitis optica, and anti-AQP4 was negative.
Query: Hello, I am a 27-year-old and was tested for neuromyelitis optica because I have symptoms of eye pain, burning sensation in my eye, and sometimes throbbing. I also have large optic nerve cupping, blurred peripheral vision, and fatigue. However, test results were negative for anti-AQP4. In addition,... Read Full »
Answer: Hi, Welcome to icliniq.com. I understand your concern. Though the detection of anti-AQP4 is one of the supportive criteria to diagnose Devic's disease (neuromyelitis optica), there are other criteria also. Absolute criteria include optic neuritis and acute myelitis. In addition, brain magnetic res... Read Full »
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