Zoledronic acid belongs to a group of drugs called bisphosphonates, which reduces the amount of calcium released into the blood from the bones. Therefore, it is used to treat hypercalcemia associated with cancer, thereby preventing fractures in bones. It is used during cancer chemotherapy treatment to prevent bone problems in cancers like multiple myeloma and cancers of the lung or breast with bony metastasis. It is administered through the intravenous route. Fever, body ache, fatigue, headache, dizziness, etc., are the ill effects of using this drug.
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Is Zoledronic acid better than Ibandronic acid for bone problem?
Query: Hi doctor, My mother is suffering with breast cancer as primary and now there is brain metastasis. The disease has spread to all the parts of the body including the bones. I have attached her PET scan for your reference. We are taking the treatment for the disease and her physical condition was ... Read Full »
Answer: Hi, Welcome to icliniq.com. I understand your concern about the patient. As per the scan report you sent (attachment removed to protect patient identity), though the metastasis is widespread, she has relatively improved as far as bone are considered (sclerotic). In case of cancers, bone quality is l... Read Full »
Query: Hello doctor.I am a 59-year-old female physician with osteoporosis. I received my first treatment last year, which was Reclast. I did not receive any anti-pyretic or anti-inflammatory medication prior to the treatment, and I had a reaction that included rigors, myalgias, esophageal spasms, and bilat... Read Full »
Answer: Hello, Welcome to icliniq.com. I read your query and understand your concern. Fever is the most common adverse effect associated with Zoledronic acid infusion. Flu-like symptoms, such as fever, chills, bone pain, arthralgias, and myalgias, are occasionally reported but typically resolve within 2... Read Full »
Had a prostate biopsy as the PSA level was high. What does the report say?
Query: Hi doctor, The patient is a 59-year-old male with whose weight is 52.3 kg and height is 166 cm. His PSA was 247.5. He had a TRUS guided biopsy, and the report is as follows. 1. Moderately differentiated adenocarcinoma. 2. Gleason grade 4+4.3. Perineural invasion present. What does the biopsy report ... Read Full »
Answer: Hi, Welcome to icliniq.com. I am sorry to know about the problem. The biopsy report says that prostate has a cancer disease. Since PSA (prostate specific antigen) is very high, it means that there is a chance that it has spread outside the prostate. The next step will be PSMA PET (prostate-specifi... Read Full »
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